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C1QC  Protein, Antibody, ELISA Kit, cDNA Clone

C1QC Related Area

C1QC Related Pathways

C1QC Summary & Protein Information

C1QC Background

Subunit structure: C1 is a calcium-dependent trimolecular complex of C1q, R and S in the molar ration of 1:2:2. C1q subcomponent is composed of nine subunits, six of which are disulfide-linked dimers of the A and B chains, and three of which are disulfide-linked dimers of the C chain.
Subcellular location: Secreted.
Post-translational: O-linked glycans consist of Glc-Gal disaccharides bound to the oxygen atom of post-translationally added hydroxyl groups.
Involvement in disease: DISEASE: Complement component C1q deficiency (C1QD) [MIM:613652]: A disorder caused by impaired activation of the complement classical pathway. It generally leads to severe immune complex disease with features of systemic lupus erythematosus and glomerulonephritis. {ECO:0000269|PubMed:8630118}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Sequence similarity: Contains 1 C1q domain. {ECO:0000255|PROSITE-ProRule:PRU00368}.; Contains 1 collagen-like domain. {ECO:0000305}.
General information above from UniProt

C1QC Alternative Name

C1QG,C1Q-C, [homo-sapiens]
C1qg,Ciqc,AI385742, [mus-musculus]
C1qg, [Rat]

C1QC Related Studies

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