BST2 (Protein|Antibody|cDNA Clone|ELISA Kit)

All BST2 reagents are produced in house and quality controlled, including 4 BST2 Antibody, 39 BST2 Gene, 1 BST2 IPKit, 4 BST2 Lysate, 4 BST2 Protein, 3 BST2 qPCR. All BST2 reagents are ready to use.

Recombinant BST2 proteins are expressed by HEK293 Cells with fusion tags as N-human IgG1-Fc, N-His.

BST2 antibodies are validated with different applications, which are IHC-P, WB, ELISA, IP.

BST2 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each BST2 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

BST2 Protein (4)

Species

BST2 Protein, Mouse, Recombinant (Fc Tag)

51043-M01H

Expression host: HEK293 Cells

Mouse BST2 Protein 12040

BST2 Protein, Mouse, Recombinant (ECD, His Tag)

51043-M07H

Expression host: HEK293 Cells

Mouse BST2 Protein 6358

BST2 Protein, Human, Recombinant (Fc Tag)

13370-H01H

Expression host: HEK293 Cells

Human BST2 Protein 10307

BST2 Protein, Human, Recombinant (His Tag)

13370-H07H

Expression host: HEK293 Cells

Human BST2 Protein 10308
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BST2 Antibody (4)

Application Clonality
Host

Anti-BST2 Antibody

13370-T60

Specificity: Human

Application: WB,ELISA,IHC-P,IP

Clonality: PAb

Human BST2 Immunohistochemistry(IHC) 4644

Anti-BST2 Antibody

13370-MM01

Specificity: Human

Application: IHC-P

Clonality: MAb

Human BST2 Immunohistochemistry(IHC) 17541

Anti-BST2 Antibody

13370-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-BST2 Antibody

107897-T08

Specificity: Chinese hamster

Application: IHC-P

Clonality: PAb

Chinese hamster BST2 Immunohistochemistry(IHC) 19478
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BST2 cDNA Clone (39)

Human
Rat
Mouse

BST2 qPCR Primer (3)

BST2 IP Kit (1)

BST2 Lysate (4)

BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demonstrated that knockdown of BST2 by siRNA inhibited cell proliferation, induced apoptosis and repressed cell motility in GC cells. In addition, the pro-tumor function of BST2 in GC was mediated partly through the NF-κB signaling. BST2 possesses the oncogenic potential in GC by regulating the proliferation, apoptosis, and migratory ability of GC cells, thereby BST2 could be a potential therapeutic target for the treatment of GC. IFN (interferon)-induced BST2 recruits the E3 ubiquitin ligase MARCH8 to catalyze the K27-linked ubiquitination of MAVS for CALCOCO2-directed autophagic degradation, hence inhibiting DDX58-mediated type I interferon signaling through a negative feedback loop. BST2 is a host protein with dual functions in response to viral infections: it traps newly assembled enveloped virions at the plasma membrane in infected cells, and it induces NF-κB activity, especially in the context of retroviral assembly. BST2 may induce or amplify proinflammatory signaling during Ebola virus infection, potentially contributing to the dysregulated cytokine response that is a hallmark of Ebola virus disease.
Protein
Antibody
Gene
qPCR
IPKit
Lysate
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