>Human Cell Expressed
>Rat BST-1 / BST1 Protein (His Tag)
|Catalog||Size (Price)||Quantity||In Stock||Operation||Other Information|
bone marrow stromal cell antigen 1 Protein Datasheet
BST1 / BST-1 Protein Price Inquiry ( Available Sizes )
BST1 / BST-1 Protein Product Information
A DNA sequence encoding the rat BST1(Q63072)(Met1-Glu293) was expressed, fused with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
BST1 / BST-1 Protein QC Testing
|Purity:||> 90 % as determined by SDS-PAGE||SDS-PAGE:
BST1 / BST-1 protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Ala 28|
The recombinant rat BST1 comprises 276 amino acids and predicts a molecular mass of 31.2 kDa. The apparent molecular mass of the recombinant protein is approximately 38-42 kDa in SDS-PAGE under reducing conditions due to glycosylation.
|Formulation:||Lyophilized from sterile PBS, pH7.4.
BST1 / BST-1 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
BST1 / BST-1 Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|CD157/BST1||Human||CD157/BST1 Protein, Recombinant||10060-H08H|
|CD157/BST1||Mouse||CD157/BST1 Protein, Recombinant||50319-M08H|
|BST1||Rat||BST-1 / BST1 Protein, Recombinant||80351-R02H|
|BST1||Rat||BST-1 / BST1 Protein, Recombinant||80351-R08H|
|Molecule||Application||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|WB, ELISA||Mouse Monoclonal Antibody||10060-MM05|
|WB, ELISA||CD157 / BST1 Antibody||10060-R029|
|WB, ELISA||Rabbit Monoclonal Antibody||10060-RP01|
|WB, ELISA||Rabbit Polyclonal Antibody (Antigen Affinity Purified)||10060-RP02|
|WB, ELISA||Rabbit Polyclonal Antibody (Antigen Affinity Purified)||50319-RP02|
BST1 / BST-1 Protein Description
CD157, also known as bone marrow sromal cell antigen 1 (BST-1), is a glycosylphosphatidylinositol-anchored ectoenzyme belonging to the NADase/ADP-ribosyl cyclase family. It is expressed in the bone marrow, spleen and thymus in lymphoid organs, and the lung, kidney and heart in non-lymphoid organs. In mouse, CD157 is also expressed on lymphoid progenitors. It has a dual nature behaving both as an ectoenzyme and as a receptor. Cross-linking of CD157 induces intracellular Ca2+ mobilization and re-shaping in neutrophils, thus regulating their adhesive and migratory properties. The CD157-mediated signals promote cell polarization, regulate chemotaxis induced through the high affinity formyl-methionyl-leucyl-phenylalanine (fMLP) receptor and control transendothelial migration. CD157 exhibits homology with CD38 and Aplysia ADP-ribosyl cyclase. Like CD38, it has both ADP-ribosyl cyclase and cADPR hydrolase activities. The CD157 gene is synthenic on 4p15 with CD38, with which it also shares a unique genomic organization. Their conservation in phylogeny is striking evidence for their relevance in the life and death cycle of the cell. CD157 has a specific and crucial role in the regulation of innate immunity during inflammation. The murine CD157 is a useful marker for lymphoid progenitor cells initiating gene rearrangement of their antigen receptors.
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