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BMP-2 Antibody, Mouse MAb

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Human BMP-2 Antibody Product Information
Immunogen:Recombinant Human BMP-2 protein (Catalog#10426-HNAE)
Clone ID:7D10G8E2
Ig Type:Mouse IgG2b
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human BMP-2 (rh BMP-2 ; Catalog#10426-HNAE; NP_001191.1; Gln 283-Arg 396). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Human BMP-2 Antibody Usage Guide
Specificity:Human BMP-2
No cross-reactivity in ELISA with
Human BMP5
E.coli cell lysate
Application:ELISA, IP

ELISA: 0.5-1 μg/mL

This antibody can be used at 0.5-1 μg/mL with the appropriate secondary reagents to detect Human BMP2. The detection limit for Human BMP2 is approximately 0.078 ng/well.

IP: 1-4 μL/mg of lysate

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Human BMP-2 Antibody IP Application Image
Other BMP-2 Antibody Products
BMP-2 Background

BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

Human BMP-2 References
  • Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6.
  • Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.
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    Catalog: 10426-MM14-200
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    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.