BAFF (Protein|Antibody|cDNA Clone|ELISA Kit)

All BAFF reagents are produced in house and quality controlled, including 5 BAFF Antibody, 40 BAFF Gene, 2 BAFF IPKit, 4 BAFF Lysate, 5 BAFF Protein, 2 BAFF qPCR. All BAFF reagents are ready to use.

Recombinant BAFF proteins are expressed by HEK293 Cells, E. coli with fusion tags as N-human IgG1-Fc, Native, N-cleavage.

BAFFantibodies are validated with different applications, which are ELISA, FCM, WB, IP.

BAFFcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each BAFF of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

BAFF Protein (5)

Species

BAFF Protein, Cynomolgus, Recombinant (Fc Tag)

90267-C01H

Expression host: HEK293 Cells

Cynomolgus BAFF/BLyS/TNFSF13B Protein 12919

BAFF Protein, Canine, Recombinant (Fc Tag)

70112-D01H

Expression host: HEK293 Cells

Canine BAFF/BLyS/TNFSF13B Protein 12302

BAFF Protein, Human, Recombinant

10056-HNAE

Expression host: E. coli

Human BAFF/BLyS/TNFSF13B Protein 8344

BAFF Protein, Human, Recombinant (Fc Tag)

10056-H01H

Expression host: HEK293 Cells

Human BAFF/BLyS/TNFSF13B Protein 8343

BAFF Protein, Human, Recombinant

10056-HNCH

Expression host: HEK293 Cells

Human BAFF/BLyS/TNFSF13B Protein 8345
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BAFF Antibody (5)

Application Clonality
Host

Anti-BAFF Antibody

10056-RP02

Specificity: Human

Application: WB,ELISA,IP

Clonality: PAb

Human BAFF/BLyS/TNFSF13B Immunoprecipitation(IP) 7942

Anti-BAFF Antibody

10056-R182

Specificity: Human

Application: WB,FCM,IP

Clonality: MAb

Human BAFF/BLyS/TNFSF13B Flow Cytometry (FC) 5336

Anti-BAFF Antibody (PE)

10056-R182-P

Specificity: Human

Application: FCM

Clonality: MAb

Human BAFF/BLyS/TNFSF13B Flow Cytometry (FC) 5335

Anti-BAFF Antibody

10056-R001

Specificity: Human

Application: ELISA

Clonality: MAb

Anti-BAFF Antibody

10056-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

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BAFF cDNA Clone (40)

Human
Mouse
Canine
Rhesus

BAFF qPCR Primer (2)

BAFF IP Kit (2)

BAFF Lysate (4)

B lymphocyte stimulator (BLyS), also known as TNFSF13B, CD257 and BAFF, is single-pass type II membrane protein, which belongs to the tumor necrosis factor family. BAFF is abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. BAFF is a cytokine and serves as a ligand for receptors TNFRSF13B (TACI), TNFRSF17 (BCMA), and TNFRSF13C (BAFFR). These receptors is a prominent factor in B cell differentiation, homeostasis, and selection. BLyS levels affect survival signals and selective apoptosis of autoantibody-producing B cells. Thus, it acts as a potent B cell activator and has been shown to play an important role in the proliferation and differentiation of B cells. Overexpression of BLyS in mice can lead to clinical and serological features of systemic lupus erythematosus (SLE) and Sjögren's syndrome (SS). BLyS as an attractive therapeutic target in human rheumatic diseases. The ability of BLyS to regulate both the size and repertoire of the peripheral B cell compartment raises the possibility that BLyS and antagonists thereof may form the basis of a therapeutic trichotomy. As an agonist, BLyS protein may enhance humoral immunity in congenital or acquired immunodeficiencies such as those resulting from viral infection or cancer therapy.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

Protein
Antibody
Gene
qPCR
IPKit
Lysate
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