All BDNF reagents are produced in house and quality controlled, including 4 BDNF Antibody, 38 BDNF Gene, 1 BDNF Lysate, 1 BDNF Protein, 2 BDNF qPCR. All BDNF reagents are ready to use.
Recombinant BDNF proteins are expressed by CHO Stable Cells with fusion tags as Native.
BDNFantibodies are validated with different applications, which are IHC-P, ELISA, WB.
BDNFcDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each BDNF of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Expression host: CHO Stable Cells
BDNF is a member of the nerve growth factor family. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.