Bcl-W / BCL2L2 Protein

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1

B4GALT1 Protein Products

B4GALT1 Protein, Recombinant

Molecule	Species	Description	Cat. No
B4GALT1/GGTB2	Human	B4GALT1/GGTB2 Protein, Recombinant	11220-H07H

B4GALT1 Antibody

Molecule	Application	Description	Cat. No
Human B4GALT1/GGTB2	WB, ELISA	B4GALT1/GGTB2 Antibody, Rabbit MAb	11220-R001
Human B4GALT1/GGTB2	WB, ELISA	Rabbit Polyclonal Antibody	11220-RP01
Human B4GALT1/GGTB2	WB, ELISA	B4GALT1/GGTB2 Antibody, Rabbit Pab (Antigen Affinity Purified)	11220-RP02
Human B4GALT1/GGTB2	WB, ELISA	B4GALT1/GGTB2 Antibody, Rabbit Pab (Antigen Affinity Purified)	10059-RP02

B4GALT1 cDNA Clone

Molecule	Species	Description	Cat. No
B4GALT1/GGTB2	Human	Homo sapiens B4GALT1/GGTB2 DNA ORF clone(NM_001497.3)	HG11220-M

B4GALT1 Related Areas

Enzyme>>Carbohydrate Metabolism Enzymes>>B4GALT1

B4GALT1 Alternative Names

B4GALT1, B4GAL-T1, GGTB2, beta4Gal-T1, DKFZp686N19253, GT1, GTB, MGC50983 [Homo sapiens]

B4GALT1, Ggtb2, Ggtb, B-1,4-GalT, RP23-135L5.6, AA407245, GalT [Mus musculus]

B4GALT1 Background

Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. B4GALT1 gene directs production of B4GALT1 protein using either of two transcription start sites. The product of the smaller transcript serves the traditional biosynthetic role in the Golgi. This form also complexes with α-lactalbumin, a mammary-specific protein, to form lactose synthase. In addition to a biosynthetic role, the protein translated from the longer transcript appears on the plasma membranes of some cells where it serves as a signalling receptor in cell-matrix interactions such as sperm-egg binding.

B4GALT1 Related Studies

1. Hennet T. (2002) The galactosyltransferase family. Cellular and Molecular Life Sciences. 59(7): 1081-95.
2. Landers EA, et al. (2009) Porcine β1, 4-Galactosyltransferase-I Sequence and Expression. Reproduction in Domestic Animals. 44(2): 228–34.
3. Amado M, et al. (2000) Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. Biochim Biophys Acta. 1473 (1): 35–53.