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B4GALT1 / GGTB2 Antibody, Rabbit PAb

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    Human B4GALT1 Antibody Product Information
    Immunogen:Recombinant Human B4GALT1 protein (Catalog#11220-H07H)
    Clone ID:
    Ig Type:Rabbit IgG
    Concentration:
    Formulation:0.2 μm filtered solution in PBS with 5% trehalose
    Preparation:Produced in rabbits immunized with purified, recombinant Human B4GALT1 / GGTB2 (rh B4GALT1; Catalog#11220-H07H; NP_001488.2; Gly 44-Ser 398).Total IgG was purified by Protein A affinity chromatography.
    Other B4GALT1 Antibody Products
    Reactivity: Human  
    Application: ELISA  
      11220-MM01-50
      11220-MM01-200
      11220-MM01-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      Reactivity: Human  
      Application: ELISA  
        11220-MM02-50
        11220-MM02-200
        11220-MM02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        Reactivity: Human  
        Application: ELISA  
          11220-RP02-50
          11220-RP02-200
          11220-RP02-100
          50 µg 
          200 µg 
          100 µg 
          Add to Cart
          Reactivity: Human  
          Application: ELISA  
            11220-R001-50
            11220-R001-100
            11220-R001-1
            50 µg 
            100 µg 
            1 mg 
            Add to Cart
            B4GALT1/GGTB2 Background

            Beta1,4-Galactosyltransferase-I (B4GALT1), one of seven beta1,4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. B4GALT1 gene directs production of B4GALT1 protein using either of two transcription start sites. The product of the smaller transcript serves the traditional biosynthetic role in the Golgi. This form also complexes with α-lactalbumin, a mammary-specific protein, to form lactose synthase. In addition to a biosynthetic role, the protein translated from the longer transcript appears on the plasma membranes of some cells where it serves as a signalling receptor in cell-matrix interactions such as sperm-egg binding.

            Human B4GALT1/GGTB2 References
          • Hennet T. (2002) The galactosyltransferase family. Cellular and Molecular Life Sciences. 59(7): 1081-95.
          • Landers EA, et al. (2009) Porcine 1, 4-Galactosyltransferase-I Sequence and Expression. Reproduction in Domestic Animals. 44(2): 228-34.
          • Amado M, et al. (2000) Identification and characterization of large galactosyltransferase gene families: galactosyltransferases for all functions. Biochim Biophys Acta. 1473 (1): 35-53.
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            Catalog: 11220-RP01-400
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            Datasheet & Documentation

            All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
            Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"