All AZU1 reagents are produced in house and quality controlled, including 5 AZU1 Antibody, 1 AZU1 ELISA, 12 AZU1 Gene, 1 AZU1 Lysate, 1 AZU1 Protein, 1 AZU1 qPCR. All AZU1 reagents are ready to use.
Recombinant AZU1 proteins are expressed by HEK293 Cells with fusion tags as C-His.
AZU1antibodies are validated with different applications, which are ELISA, ELISA(Cap).
AZU1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each AZU1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
AZU1ELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is not a serine proteinase since the active site serine and histidine residues are replaced. Neutrophils arriving first at sites of inflammation release Azurocidin, which acts in a paracrine fashion on endothelial cells causing the development of intercellular gaps and allowing leukocyte extravasation. It thus be regarded as a reasonable therapeutic target for a variety of inflammatory disease conditions.