ApoA1 Protein Price Inquiry ( Available Sizes )
ApoA1 Protein Product Information
A DNA sequence encoding the mouse ApoA1 (Q00623) (Met1- Gln264) was expressed with a C-terminal polyhistidine tag.
ApoA1 Protein QC Testing
||>94% as determined by SDS-PAGE
||< 1.0 EU per μg of the protein as determined by the LAL method
||Samples are stable for up to twelve months from date of receipt at -70℃
|Predicted N terminal:
The recombinant mouse ApoA1 comprises 257 amino acids and has a predicted molecular mass of 30.2 kDa. The apparent molecular mass of the protein is approximately 27-31 kDa in SDS-PAGE under reducing conditions due to glycosylation.
||Lyophilized from sterile PBS, pH7.4.
- Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
- Please contact us for any concerns or special requirements.
ApoA1 Protein Usage Guide
||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
ApoA1 Protein Related Products & Topics
ApoA1 Protein Description
Apolipoprotein A1 (APOA1) is the main component of high density lipoprotein (HDL) in plasma and is involved in the esterification of cholesterol as a cofactor of lecithin-cholesterol acyltransferase(LCAT) which is responsible for the formation of most plasma cholesteryl esters. and thus play a major role in cholesterol efflux from peripheral cells. APOA1 is also characterized as a prostacyclin stabilizing factor, and thus may have an anticlotting effect. Defects in encoding gene may result in HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. As a major component of the HDL complex, APOA1 helps to clear cholesterol from arteries. Men carrying a mutation may develop premature coronary artery disease.
- Toptas B. et al., 2011, In Vivo. 25 (3): 425-30.
- Haase CL. et al., 2011, J Intern Med. 270 (2): 136-46.
- Wu Z. et al., 2011, J Biol Chem. 286 (14): 12495-508.