- EGFR Signaling Pathway
- TGF-beta Signaling
- Canonical Wnt Signaling
- non-Canonical Wnt Signaling
- Notch Signaling
- p53 Pathway
- NF-kB Pathway
- Cytokine Signaling
>Antibody Purification Platform
Antibody Purification Platform
Sino Biological Inc.
Your Centralized Protein / Antibody Development / Production Lab
Attractive Cost Saving for Products & Services
Sino Biological has developed a very comprehensive set of antibody & Fab purification technologies.
Experience & Past Track Records:
- In the past two years, we have successfully purified over 400 monoclonal antibodies at scales from mg to 100 grams.
- Over 100 therapeutic monoclonal antibody candidates were purified at high quality (high monomer purity and low endotoxin level) for pre-clinical in vivo animal testing.
- We have a team of purification experts with extensive hands-on experiences and expertise in handling different subtypes of antibodies from different species.
Capabilities & Capacities:
- Expertise in purifying antibodies for various applications.
- Expertise in removing antibody aggregates and fragments.
- Expertise in removing endotoxin to <0.1 EU/mg.
- Expertise in purifying monoclonal antibodies for pre-clinical animal studies requiring high product quality.
- Expertise in UF, MF, DF, TFF, Protein A/G, AEX, CEX, HIC, SEC.
- High throughput antibody purification systems.
- Large scale purification columns (5-10L resins).
- Extensive experience in purification process scale-up: from 10ml to 100L.
- Hundreds of antibodies purified each year.
Types of Antibody Purified In the Past
- Human Antibodies: IgG1, IgG2, IgG3, IgG4, IgM.
- Mouse Antibodies: IgG1, IgG2a, IgG2b, IgG3, IgM.
- Rat Antibodies: IgG1, IgG2.
- Rabbit Antibodies: monoclonal antibody and polyclonal antibody.
- Canine Antibodies: monoclonal antibody.
- Bovine Antibodies: polyclonal antibodies.
- HEK293 Transient Transfection Platform for Recombinant Protein & Antibody Production.
- CHO Transient Transfection Platform for Recombinant Protein & Antibody Production.
- CHO Stable Cell Line Platform for Recombinant Protein & Antibody Production.
- Bacterial (E. Coli.) Platform for Recombinant Protein Expression & Production.
- Baculovirus Insect Cell Platform for Recombinant Protein Expression & Production.
- Protein Purification Platform for Recombinant Protein Bulk Production.