Anti-mouse SFTPD / PSPD / COLEC7 antibody
| Catalog | Size (Price) | Quantity | In Stock | Operation | Other Information |
| 50205-RP01 |
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Mouse Pulmonary-Associated Protein D ( SFTPD / PSPD / COLEC7 ) Antibody
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Order or Inquire for SFTPD Antibody product |  |
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Detection limit is 0.039 ng/well in ELISA |
SFTPD / PSPD / COLEC7 Antibody Product Information
| Immunogen : |
Recombinant mouse SFTPD protein ( Catalog#50205-M08H ) |
| Antibody Type : | Rabbit Polyclonal Antibody ( Antibody Purification Platform ) |
| Ig Type : |
Rabbit IgG |
| Formulation : | 0.2 μm filtered solution in PBS with 5% trehalose |
| Preparation : |
Produced in rabbits immunized with purified, human cell-derived, recombinant mouse SFTPD ( rM SFTPD ; Catalog#50205-M08H ; NP_033186.1 ; Met 1-Phe 374 ). Total IgG was purified by Protein A affinity chromatography. |
SFTPD / PSPD / COLEC7 Antibody Usage Guide
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Specificity : |
Mouse SFTPD / PSPD / COLEC7 |
| Western blot : | This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect mouse SFTPD in WB |
| Direct ELISA : | This antibody can be used at 0.5 -1.0 μg/mL with the appropriate secondary reagents to detect mouse SFTPD. The detection limit for mouse SFTPD is 0.039 ng/well |
| Storage : | This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles. |
SFTPD / PSPD / COLEC7 Antibody Related Products & Topics
Related Areas:
Immunology>>Adhesion Molecule>>Lectin>>SFTPD/SP-D/SFTP4
Immunology>>Innate Immunity>>Acute Phase Proteins>>SFTPD/SP-D/SFTP4
Proteins:
| Molecule | Species | Description //For Detailed Info.------CLICK! | Cat No | Size/Price |
| SFTPD/SP-D/SFTP4 | Mouse | SFTPD Protein, Recombinant | 50205-M08H | 100µg($290) ; Order |
Antibodies:
| Molecule | Application | Description //For Detailed Info.------CLICK! | Cat No | Size/Price |
| Mouse SFTPD/SP-D/SFTP4 |
WB, ELISA | Rabbit Polyclonal Antibody | 50205-RP01 | Order |
| Mouse SFTPD/SP-D/SFTP4 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) | 50205-RP02 | 100µg($250); Order |
SFTPD / PSPD / COLEC7 Antibody Background
Surfactant, pulmonary-associated protein D, also known as SFTPD and SP-D, is a member of the collectin family of C-type lectins that is synthesized in many tissues including respiratory epithelial cells in the lung, and contains one C-type lectin domain and one collagen-like domain. SP-D is assembled predominantly as dodecamers consisting of four set of homotrimers stabilized by interchain disulfide bonds involving two conserved amino-terminal cysteine residues. SP-D is produced primarily by alveolar type II cells and nonciliated bronchiolar cells in the lung and is constitutively secreted into the alveoli where it influences surfactant homeostasis, effector cell functions, and host defense. It is upregulated in a variety of inflammatory and infectious conditions including Pneumocystis pneumonia, asthma, and bleomycin injury. Mice or rats exposed to hyperoxic challenge also have increases in SP-D, suggesting that it may have a role in protection from this insult.
References
- Liu, Y. et al., 1994, J. Immunol. 152:1821-1829.
- Kotenko, S.V. et al.,1997, EMBO J. 16 (19): 5894-5903.
- Gibbs, V. C. et al., 1997, Pennica. Gene 186: 97-101.
- Kotenko, S.V. et al., 2001, J. Biol. Chem. 276: 2725-2732.
- Crepaldi, L. et al., 2001, J. Immunol. 167: 2312-2322.
- Dinant, S. J. et al., 2007, Surg Res. 141 (2): 176-82.
