Angiotensinogen Protein, Antibody, ELISA Kit, Gene cDNA Clone

Sino Biological Inc. — Biological Solution Specialist

Protein, Antibody, ELISA Kit, cDNA Clone – All Produced in House

With multiple advanced technology platforms and large scale capacities, Sino Biological has quickly emerging as a leader in life science research tool developer worldwide.(more)

Our recombinant proteins span wide species: human, mouse, rat, dog, monkey, bovine, as well as major viral proteins, such as influenza, HIV, RSV, CMV, etc. All our proteins are manufactured in bulk quantities using sequence verified vectors and state-of-the-art mammalian, insect, or E. coli expression processes. (Know more about our proteins)
We offer primary antibodies (rabbit Mabs, mouse Mabs, rabbit Pabs), secondary antibodies, tag antibodies, and control antibodies, making us one of the most comprehensive antibody reagent providers in the industry. We are the first company that is able to generate 2^nd generation rabbit Mabs. Owning to our creative proprietary technology, we produce high-affinity antibodies with 10-150 fold improvement in ELISA detection limit compared with antibodies of the leading brand. (Know more about our antibodies)
All reagents are available in both small retails and bulk packages - both offering 30-80% cost saving compared to currently leading brands. We installed the same quality requirement and assurance for preclinical products to reagent products, hence the quality of Sino Biological products is typically higher than that of other reagent providers.

Angiotensinogen Protein, Antibody, ELISA Kit, cDNA Clone Products

All Angiotensinogen Products list

• Angiotensinogen Protein

  Human Angiotensinogen/SerpinA8 Protein, Recombinant	10994-H08H
  Mouse Angiotensinogen/SerpinA8 Protein, Recombinant	50337-M08H

• Angiotensinogen Antibody

  Angiotensinogen Antibody, Mouse MAb (Biotin conjugated)	10994-MM01
  Angiotensinogen/SerpinA8 Antibody, Rabbit MAb	10994-R001
  Angiotensinogen Antibody, Rabbit PAb	10994-RP01
  Angiotensinogen Antibody, Rabbit PAb (Antigen Affinity Purified)	10994-RP02
  Angiotensinogen / SerpinA8 / AGT Antibody (Antigen Affinity Purified)	50337-RP02

• Angiotensinogen ELISA Kit

• Angiotensinogen cDNA Clone

  Homo sapiens Angiotensinogen/SerpinA8 cDNA Clone

  HG10994-M

Browse Angiotensinogen Protein, Antibody, ELISA Kit, cDNA Clone Products by Following Categories

Angiotensinogen Protein, Antibody, ELISA Kit, cDNA Clone

• Angiotensinogen Protein

  – Human Angiotensinogen Protein

  – Mouse Angiotensinogen Protein

  – Rat Angiotensinogen Protein

  – Rhesus Angiotensinogen Protein

  – Cynomolgus Angiotensinogen Protein

  – Canine (Dog) Angiotensinogen Protein

  – Ferret Angiotensinogen Protein

  – Bovine Angiotensinogen Protein

• Angiotensinogen Antibody

  – Human Angiotensinogen Antibody

  – Mouse Angiotensinogen Antibody

  – Rat Angiotensinogen Antibody

  – Rhesus Angiotensinogen Antibody

  – Cynomolgus Angiotensinogen Antibody

  – Canine (Dog) Angiotensinogen Antibody

  – Ferret Angiotensinogen Antibody

  – Bovine Angiotensinogen Antibody

• Angiotensinogen ELISA Kit

  – Human Angiotensinogen ELISA Kit

  – Mouse Angiotensinogen ELISA Kit

  – Rat Angiotensinogen ELISA Kit

  – Rhesus Angiotensinogen ELISA Kit

  – Cynomolgus Angiotensinogen ELISA Kit

  – Canine (Dog) Angiotensinogen ELISA Kit

  – Ferret Angiotensinogen ELISA Kit

  – Bovine Angiotensinogen ELISA Kit

• Angiotensinogen cDNA Clone

  – Human Angiotensinogen cDNA Clone

  – Mouse Angiotensinogen cDNA Clone

  – Rat Angiotensinogen cDNA Clone

  – Rhesus Angiotensinogen cDNA Clone

  – Cynomolgus Angiotensinogen cDNA Clone

  – Canine (Dog) Angiotensinogen cDNA Clone

  – Ferret Angiotensinogen cDNA Clone

  – Bovine Angiotensinogen cDNA Clone

Antibody to Angiotensinogen

• ELISA Antibody to Angiotensinogen

  – ELISA Antibody to Human Angiotensinogen

  – ELISA Antibody to Mouse Angiotensinogen

  – ELISA Antibody to Rat Angiotensinogen

  – ELISA Antibody to Rhesus Angiotensinogen

  – ELISA Antibody to Cynomolgus Angiotensinogen

  – ELISA Antibody to Canine (Dog) Angiotensinogen

  – ELISA Antibody to Ferret Angiotensinogen

  – ELISA Antibody to Bovine Angiotensinogen

• Western Blot Antibody to Angiotensinogen

  – Western Blot Antibody to Human Angiotensinogen

  – Western Blot Antibody to Mouse Angiotensinogen

  – Western Blot Antibody to Rat Angiotensinogen

  – Western Blot Antibody to Rhesus Angiotensinogen

  – Western Blot Antibody to Cynomolgus Angiotensinogen

  – Western Blot Antibody to Canine (Dog) Angiotensinogen

  – Western Blot Antibody to Ferret Angiotensinogen

  – Western Blot Antibody to Bovine Angiotensinogen

• Immunohistochemistry (IHC) Antibody to Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Human Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Mouse Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Rat Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Rhesus Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Cynomolgus Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Canine (Dog) Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Ferret Angiotensinogen

  – Immunohistochemistry (IHC) Antibody to Bovine Angiotensinogen

• Flow Cytometry (FACS) Antibody to Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Human Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Mouse Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Rat Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Rhesus Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Cynomolgus Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Canine (Dog) Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Ferret Angiotensinogen

  – Flow Cytometry (FACS) Antibody to Bovine Angiotensinogen

Summary for Angiotensinogen

Angiotensinogen, also known as AGT and SerpinA8, is a member of the serpin family. It is an α-2-globulin that is produced constitutively and released into the circulation mainly by the liver. Angiotensinogen is a essential component of the renin-angiotensin system (RAS) and a potent regulator of blood pressure. Angiotensinogen can be schematically considered to consist of a combination of an angiotensin I (Ang I) function, located at the N-terminal end, and the presence of a serpin (serine protease inhibitor) structure at the opposite end. Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3, angiotensin-4. Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2. Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system. Defects in AGT are associated with susceptibility to essential hypertension and renal tubular dysgenesis (RTD). Several serpins (antithrombin, maspin, pigment epithelial-derived factor, and kallistatin) have been recently shown to exert an antiangiogenic activity, suggesting a common mechanism of endothelial cell proliferation and migration. Angiotensinogen/AGT and its renin-cleaved product, des(Ang I)AGT, are also angiogenesis inhibitors, both in vitro and in vivo at concentrations within the range of those observed in plasma. The Angiotensinogen products, that is angiotensin II and possibly angiotensin II-related products, have been found to act locally in modulating adipose tissue growth in an autocrine/paracrine manner. The transient or chronic overexpression of angiotensinogen in adipose tissue favors lipogenesis in adipocytes and leads to a 'vicious' circle whereby adipose tissue development is further increased.

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