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>Human Cell Expressed
>Human Alpha-2-glycoprotein / AZGP1 Protein (His Tag)
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Alpha-2-glycoprotein 1, zinc-binding Protein Datasheet
Alpha-2-glycoprotein / AZGP1 Protein Price Inquiry ( Available Sizes )
Alpha-2-glycoprotein / AZGP1 Protein Product Information
|Synonym :||AZGP1, ZAG, ZNGP1|
A DNA sequence encoding the human AZGP1 (P25311) (Met1-Ser298) with a C-terminal polyhistidine tag was expressed.
|Expression Host:||Human Cells|
Alpha-2-glycoprotein / AZGP1 Protein QC Testing
|Purity:||> 95 % as determined by SDS-PAGE||SDS-PAGE:
Alpha-2-glycoprotein / AZGP1 protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||Gln 21|
The recombinant human AZGP1 comprises 289 amino acids and has a predicted molecular mass of 33.6 kDa. The apparent molecular mass of the protein is approximately 41 kDa in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH7.4.
Alpha-2-glycoprotein / AZGP1 Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
Alpha-2-glycoprotein / AZGP1 Protein Related Products & Topics
Alpha-2-glycoprotein / AZGP1 Protein Description
Alpha-2-glycoprotein, also known as AZGP1, is a member of the MHC class I family. It has been identified as a novel adipokine since it is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia. Alpha-2-glycoprotein can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein may bind polyunsaturated fatty acids. It can cause the extensive fat loss associated with some advanced cancer.
- Tada T. et al., 1991, J Histochem Cytochem. 39 (9): 1221-6.
- Vanni H. et al., 2009, Chest. 135 (5): 1197-208.
- Ueyama H. et al., 1991, Biochem Biophys Res Commun. 177 (2): 696-703.