Anti-Zinc Alpha 2 Glycoprotein Antibody (Rabbit Polyclonal antibody) General Information
Anti-Zinc Alpha 2 Glycoprotein Antibody
Reacts with: Human
Human Zinc Alpha 2 Glycoprotein
Recombinant Human Alpha-2-glycoprotein / AZGP1 protein (Catalog#13242-H08H)
Produced in rabbits immunized with purified, recombinant Human Alpha-2-glycoprotein / AZGP1 (rh Alpha-2-glycoprotein / AZGP1; Catalog#13242-H08H; P25311; Met1-Ser298). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-Zinc Alpha 2 Glycoprotein Antibody (Rabbit Polyclonal antibody) Validated Applications
**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
Anti-Zinc Alpha 2 Glycoprotein Antibody Alternative Names
Anti-ZA2G Antibody;Anti-ZAG Antibody
Zinc Alpha 2 Glycoprotein Background Information
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia.
alpha-2-glycoprotein 1, zinc-binding
Tada T, et al. (1991) Immunohistochemical localization of Zn-alpha 2-glycoprotein in normal human tissues. J Histochem Cytochem. 39(9):1221-6.Vanni H, et al. (2009) Cigarette Smoking Induces Overexpression of a Fat-Depleting Gene AZGP1 in the Human. Chest. 135(5):1197-208.Ueyama H, et al. (1991) Cloning and nucleotide sequence of a human Zn-alpha 2-glycoprotein cDNA and chromosomal assignment of its gene. Biochem Biophys Res Commun. 177(2):696-703.