Adiponectin Protein & Antibody (Acrp30, ADIPOQ)

30 kDa adipocyte complement-related protein / Adiponectin, C1Q and collagen domain containing

Adiponectin Products

Adiponectin Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Acrp30/ADIPOQ	Human	ADIPOQ / ACDC Protein, Recombinant	10772-H02H
Acrp30/ADIPOQ	Mouse	Adiponectin/Acrp30/ADIPOQ Protein, Recombinant	50636-M08H

Adiponectin Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Mouse Acrp30/ADIPOQ	WB, ELISA	Adiponectin/Acrp30/ADIPOQ Antibody, Rabbit PAb	50636-RP01
Mouse Acrp30/ADIPOQ	WB, ELISA	Adiponectin/Acrp30/ADIPOQ Antibody, Rabbit PAb (Antigen Affinity Purified)	50636-RP02
Mouse Acrp30/ADIPOQ	WB, ELISA	Adiponectin/Acrp30/ADIPOQ Antibody, Rabbit MAb	50636-R038

Adiponectin cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
Acrp30/ADIPOQ	Human	Homo sapiens Adiponectin/Acrp30/ADIPOQ cDNA Clone	HG10772-M
Acrp30/ADIPOQ	Mouse	Mus musculus Adiponectin/Acrp30/ADIPOQ cDNA Clone	MG50636-M

Adiponectin Related Areas

Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>Adiponectin/Acrp30/ADIPOQ

Adiponectin Alternative Names

Adiponectin, ACRP30, ADIPOQ, ACDC, ADIPQTL1, ADPN, APM-1, APM1, GBP28 [Homo sapiens]

Adiponectin, Acrp30, Adipoq, 30kDa, APN, Acdc, GBP28, adipo, apM1 [Mus musculus]

Adiponectin Background

Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other tissues. Adiponectin mediates its actions in the periphery mainly via two receptors, AdipoR1 and AdipoR2. Adiponectin influences gonadotropin release, normal pregnancy, and assisted reproduction outcomes. Adiponectin, a beneficial adipokine, represents a major link between obesity and reproduction. Higher levels of adiponectin are associated with improved menstrual function and better outcomes in assisted reproductive cycles. Unlike other adipocytokines produced by adipose tissue, adiponectin appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. Additionally, it is important factor in chronic liver diseases and chronic kidney diseases. Some cancer cell types express adiponectin receptors. Thus Adiponectin may act on tumour cells directly by binding and activating adiponectin receptors and downstream signalling pathways.

Adiponectin Related Studies

1. Cui J, et al. (2011) The role of adiponectin in metabolic and vascular disease: a review. Clin Nephrol. 75(1): 26-33.
2. Michalakis KG, et al. (2010) The role of adiponectin in reproduction: from polycystic ovary syndrome to assisted reproduction. Fertil Steril. 94(6): 1949-57.
3. Díez JJ, et al.. (2010) The role of the novel adipocyte-derived protein adiponectin in human disease: an update. Mini Rev Med Chem. 10(9): 856-69.
4. Ouchi N, et al. (2007) Adiponectin as an anti-inflammatory factor. Clin Chim Acta. 380(1-2): 24-30.
5. Barb D, et al. (2006) Adiponectin: a link between obesity and cancer. Expert Opin Investig Drugs. 15(8): 917-31.