Adiponectin / Acrp30 / ADIPOQ Antibody (Cytokine)

Adiponectin / Acrp30 / ADIPOQ Antibody Datasheet

Adiponectin / Acrp30 / ADIPOQ Antibody Product Information

• Immunogen: Recombinant Mouse ADIPOQ protein (Catalog#50636-M08H)
• Antibody Type: Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
• Clone ID: 038
• Ig Type: Rabbit IgG
• Formulation: 0.2 μm filtered solution in PBS with 5% trehalose
• Preparation: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Adiponectin / Acrp30 / ADIPOQ (rM Adiponectin / Acrp30 / ADIPOQ; Catalog#50636-M08H; NP_033735.3; Met 1-Asn 247).

Adiponectin / Acrp30 / ADIPOQ Antibody Usage Guide

• Specificity: Mouse Adiponectin / Acrp30 / ADIPOQ
• Direct ELISA: This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Mouse ADIPOQ1. The detection limit for Mouse ADIPOQ1 is approximately 0.0049 ng/well.
• Storage: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
  Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

Adiponectin / Acrp30 / ADIPOQ Antibody Background

Adiponectin (ADIPOQ), also known as Adipocyte, C1q and collagen domain-containing protein, 30 kDa adipocyte complement-related protein, adipocyte complement-related 30 kDa protein, adipose most abundant gene transcript 1 protein, gelatin-binding protein, ADIPOQ and ACDC, is a secreted protein which contains oneC1q domain and onecollagen-like domain. Adiponectin/Acrp30/ADIPOQ is an important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin/Acrp30/ADIPOQ stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin/Acrp30/ADIPOQ antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Adiponectin/Acrp30/ADIPOQ inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. It may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.

References

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