Acetylcholinesterase Protein, Antibody, ELISA Kit, cDNA Clone

Sino Biological Inc. — Biological Solution Specialist

Protein, Antibody, ELISA Kit, cDNA Clone – All Produced in House

With multiple advanced technology platforms and large scale capacities, Sino Biological has quickly emerging as a leader in life science research tool developer worldwide.(more)

Our recombinant proteins span wide species: human, mouse, rat, dog, monkey, bovine, as well as major viral proteins, such as influenza, HIV, RSV, CMV, etc. All our proteins are manufactured in bulk quantities using sequence verified vectors and state-of-the-art mammalian, insect, or E. coli expression processes. Over 80% recombinant proteins are human cell-expressed. (Know more about our proteins)
We offer primary antibodies (rabbit Mabs, mouse Mabs, rabbit Pabs), secondary antibodies, tag antibodies, and control antibodies, making us one of the most comprehensive antibody reagent providers in the industry. We are the first company that is able to generate 2^nd generation rabbit Mabs. Owning to our creative proprietary technology, we produce high-affinity antibodies with 10-150 fold improvement in ELISA detection limit compared with antibodies of the leading brand. (Know more about our antibodies)
All reagents are available in both small retails and bulk packages - both offering 30-80% cost saving compared to currently leading brands. We installed the same quality requirement and assurance for preclinical products to reagent products, hence the quality of Sino Biological products is typically higher than that of other reagent providers.

Acetylcholinesterase Protein, Antibody, ELISA Kit, cDNA Clone Products

All Acetylcholinesterase Products list

• Acetylcholinesterase Protein

  Mouse Acetylcholinesterase/ACHE Protein

  50543-M08H

• Acetylcholinesterase Antibody

  Acetylcholinesterase / ACHE Antibody	50543-RP01
  Acetylcholinesterase / ACHE Antibody (Antigen Affinity Purified)	50543-RP02

• Acetylcholinesterase ELISA Kit

• Acetylcholinesterase cDNA Clone

  Mus musculus Acetylcholinesterase/ACHE cDNA Clone

  MG50543-M

Browse Acetylcholinesterase Protein, Antibody, ELISA Kit, cDNA Clone Products by Following Categories

Acetylcholinesterase Protein, Antibody, ELISA Kit, cDNA Clone

• Acetylcholinesterase Protein

  – Human Acetylcholinesterase Protein

  – Mouse Acetylcholinesterase Protein

  – Rat Acetylcholinesterase Protein

  – Rhesus Acetylcholinesterase Protein

  – Cynomolgus Acetylcholinesterase Protein

  – Canine (Dog) Acetylcholinesterase Protein

  – Ferret Acetylcholinesterase Protein

  – Bovine Acetylcholinesterase Protein

• Acetylcholinesterase Antibody

  – Human Acetylcholinesterase Antibody

  – Mouse Acetylcholinesterase Antibody

  – Rat Acetylcholinesterase Antibody

  – Rhesus Acetylcholinesterase Antibody

  – Cynomolgus Acetylcholinesterase Antibody

  – Canine (Dog) Acetylcholinesterase Antibody

  – Ferret Acetylcholinesterase Antibody

  – Bovine Acetylcholinesterase Antibody

• Acetylcholinesterase ELISA Kit

  – Human Acetylcholinesterase ELISA Kit

  – Mouse Acetylcholinesterase ELISA Kit

  – Rat Acetylcholinesterase ELISA Kit

  – Rhesus Acetylcholinesterase ELISA Kit

  – Cynomolgus Acetylcholinesterase ELISA Kit

  – Canine (Dog) Acetylcholinesterase ELISA Kit

  – Ferret Acetylcholinesterase ELISA Kit

  – Bovine Acetylcholinesterase ELISA Kit

• Acetylcholinesterase cDNA Clone

  – Human Acetylcholinesterase cDNA Clone

  – Mouse Acetylcholinesterase cDNA Clone

  – Rat Acetylcholinesterase cDNA Clone

  – Rhesus Acetylcholinesterase cDNA Clone

  – Cynomolgus Acetylcholinesterase cDNA Clone

  – Canine (Dog) Acetylcholinesterase cDNA Clone

  – Ferret Acetylcholinesterase cDNA Clone

  – Bovine Acetylcholinesterase cDNA Clone

Antibody to Acetylcholinesterase

• ELISA Antibody to Acetylcholinesterase

  – ELISA Antibody to Human Acetylcholinesterase

  – ELISA Antibody to Mouse Acetylcholinesterase

  – ELISA Antibody to Rat Acetylcholinesterase

  – ELISA Antibody to Rhesus Acetylcholinesterase

  – ELISA Antibody to Cynomolgus Acetylcholinesterase

  – ELISA Antibody to Canine (Dog) Acetylcholinesterase

  – ELISA Antibody to Ferret Acetylcholinesterase

  – ELISA Antibody to Bovine Acetylcholinesterase

• Western Blot Antibody to Acetylcholinesterase

  – Western Blot Antibody to Human Acetylcholinesterase

  – Western Blot Antibody to Mouse Acetylcholinesterase

  – Western Blot Antibody to Rat Acetylcholinesterase

  – Western Blot Antibody to Rhesus Acetylcholinesterase

  – Western Blot Antibody to Cynomolgus Acetylcholinesterase

  – Western Blot Antibody to Canine (Dog) Acetylcholinesterase

  – Western Blot Antibody to Ferret Acetylcholinesterase

  – Western Blot Antibody to Bovine Acetylcholinesterase

• Immunohistochemistry (IHC) Antibody to Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Human Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Mouse Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Rat Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Rhesus Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Cynomolgus Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Canine (Dog) Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Ferret Acetylcholinesterase

  – Immunohistochemistry (IHC) Antibody to Bovine Acetylcholinesterase

• Flow Cytometry (FACS) Antibody to Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Human Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Mouse Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Rat Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Rhesus Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Cynomolgus Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Canine (Dog) Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Ferret Acetylcholinesterase

  – Flow Cytometry (FACS) Antibody to Bovine Acetylcholinesterase

Summary for Acetylcholinesterase

Acetylcholinesterase, also known as ACHE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. Acetylcholinesterase plays a crucial role in nerve impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter acetylcholine (ACh). Acetylcholinesterase appears to be a potential therapeutic target at muscle injuries including organophosphate myopathy. It is an externally oriented membrane-bound enzyme and its main physiological role is termination of chemical transmission at cholinergic synapses and secretory organs by rapid hydrolysis of the neurotransmitter acetylcholine (ACh). Nevertheless, it is well known that cyclophosphamide (CP; nitrogen mustard derivative) is an eminent anticancer drug. Acetylcholinesterase plays important roles in the cholinergic system, and its dysregulation is involved in a variety of human diseases. Acetylcholinesterase was significantly down-regulated in the cancerous tissues of 69.2% of hepatocellular carcinoma (HCC) patients, and the low Acetylcholinesterase expression in HCC was correlated with tumor aggressiveness, an elevated risk of postoperative recurrence, and a low survival rate. Both the recombinant Acetylcholinesterase protein and the enhanced expression of Acetylcholinesterase significantly inhibited HCC cell growth in vitro and tumorigenicity in vivo. Acetylcholinesterase as a tumor growth suppressor in regulating cell proliferation, the relevant signaling pathways, and the drug sensitivity of HCC cells. Thus, Acetylcholinesterase is a promising independent prognostic predictor for HCC recurrence and the survival of HCC patients. Acetylcholinesterase is responsible for the hydrolysis of acetylcholine in the nervous system. It is inhibited by organophosphate and carbamate pesticides. However, this enzyme is only slightly inhibited by organophosphorothionates.

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