ART1 (Protein|Antibody|cDNA Clone|ELISA Kit)

All ART1 reagents are produced in house and quality controlled, including 3 ART1 Antibody, 40 ART1 Gene, 1 ART1 Lysate, 1 ART1 Protein, 2 ART1 qPCR. All ART1 reagents are ready to use.

Recombinant ART1 proteins are expressed by HEK293 Cells with fusion tags as C-His.

ART1 antibodies are validated with different applications, which are ELISA, IHC-P.

ART1 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ART1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

ART1 Protein (1)

Species

ART1 Protein, Cynomolgus, Recombinant (His Tag)

90271-C08H

Expression host: HEK293 Cells

Cynomolgus ART1 / CD296 / ARTC1 Protein 12924
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ART1 Antibody (3)

Application Clonality
Host

Anti-ART1 Antibody

90271-RP01

Specificity: Cynomolgus

Application: ELISA

Clonality: PAb

Anti-ART1 Antibody

101925-T08

Specificity: Mouse

Application: IHC-P

Clonality: PAb

Mouse ART1 / CD296 / ARTC1 Immunohistochemistry(IHC) 14065

Anti-ART1 Antibody

90271-T24

Specificity: Cynomolgus

Application: ELISA,IHC-P

Clonality: PAb

Cynomolgus ART1 / CD296 / ARTC1 Immunohistochemistry(IHC) 4807
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ART1 cDNA Clone (40)

Mouse
Rhesus
Rat
Human

ART1 qPCR Primer (2)

ART1 Lysate (1)

Mono-ADP-ribosyltransferase (ART) 1 belongs to a family of mammalian ectoenzymes that catalyze the transfer of ADP-ribose from NAD+ to a target protein. ART1 is predominantly expressed in skeletal and cardiac muscle. It ADP-ribosylates alpha7-integrin which together with beta1-integrin forms a dimer and binds to laminin, a protein of the extracellular matrix involved in cell adhesion. This posttranslational modification leads to an increased laminin binding affinity. The differentiation-dependent upregulation of ART1 mRNA is induced by the binding of myogenin to an E box and of MEF-2 to an A/T-rich element in the proximal promoter region of the ART1 gene. Colorectal carcinoma is one of the most common cancers world-wide, with high morbidity and mortality rates. Arginine ADP-ribosyltransferase 1(ART1) is an important ecto-ADP-ribose transferase and has been proven to be intimately involved in a number of biological processes. The molecular mechanism for the function of ART1 in colorectal carcinoma and defines a potential therapeutic target for the enhanced treatment of this prominent world-wide disease
Protein
Antibody
Gene
qPCR
Lysate
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