All Arginase reagents are produced in house and quality controlled, including 3 Arginase Antibody, 40 Arginase Gene, 2 Arginase IPKit, 2 Arginase Lysate, 2 Arginase Protein, 2 Arginase qPCR. All Arginase reagents are ready to use.
Recombinant Arginase proteins are expressed by HEK293 Cells with fusion tags as C-His, N-His & C-Myc.
Arginaseantibodies are validated with different applications, which are FCM, ELISA, WB, IHC-P, IP.
ArginasecDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Arginase of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.