>Human Cell Expressed
>APCS / PTX2 / Serum amyloid P component Protein (His Tag)
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Amyloid P component, serum Protein Datasheet
APCS / PTX2 / Serum amyloid P component Protein Price Inquiry ( Available Sizes )
APCS / PTX2 / Serum amyloid P component Protein Product Information
|Synonym :||APCS, PTX2|
A DNA sequence encoding the human APCS (P02743) (Met1-Val223) was expressed with a polyhistidine tag at the C-terminus.
|Expression Host:||Human Cells|
APCS / PTX2 / Serum amyloid P component Protein QC Testing
|Purity:||> 95% as determined by SDS-PAGE||SDS-PAGE:
APCS / PTX2 / Serum amyloid P component protein
|Endotoxin:||< 1.0 EU per μg of the protein as determined by the LAL method|
|Stability:||Samples are stable for up to twelve months from date of receipt at -70℃|
|Predicted N terminal:||His 20|
The recombinant human APCS consists of 215 amino acids and predicts a molecular mass of 24.7 KDa. It migrates as an approximately 31 KDa band in SDS-PAGE under reducing conditions.
|Formulation:||Lyophilized from sterile PBS, pH 7.4.
APCS / PTX2 / Serum amyloid P component Protein Usage Guide
|Storage:||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution:||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.|
APCS / PTX2 / Serum amyloid P component Protein Related Products & Topics
|Molecule||Species||Description //For Detailed Info. and Price------CLICK!||Cat. No|
|Serum Amyloid P Component/SAP||Human||APCS / PTX2 / Serum amyloid P component Protein, Recombinant||13610-H08H|
|Serum Amyloid P Component/SAP||Mouse||Serum amyloid P component/SAP Protein, Recombinant||50113-M08H|
|Serum Amyloid P Component/SAP||Rat||Serum amyloid P component / APCS Protein, Recombinant||80061-R08H|
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|Mouse Serum Amyloid P Component/SAP||ELISA||Serum amyloid P component / APCS Antibody (Antigen Affinity Purified)||50113-RP02|
APCS / PTX2 / Serum amyloid P component Protein Description
Serum amyloid P component (SAP), also known as APCS AND Ptx2, is a 25kDa pentameric protein first identified as the pentagonal constituent of pathological deposits called "amyloid". SAP is a member of the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. SAP has a marked inhibitory effect on the proliferative response of lymphocytes to a variety of T-dependent mitogens. In addition, SAP enhances the formation of active E rosettes, a marker of activated T cells. SAP has certain sequence homology with C-reactive protein (CRP), a classical acute phase response plasma protein, and both of which are evolutionary conserved in all vertebrates and also found in distant invertebrates.
- Cathcart, E. S. et al.,1967, Biochim. Biophy. Acta. 147: 392-3.
- Levo,Y. et al., 1985, Int Arch Allergy Appl Immunol. 77 (3): 322-5.
- Emsley, J. et al., 1994, Nature. 367 (6461): 338-45.
- Pepys, M. B. et al.,1997,Amyloid-International Journal of Experimental and Clinical Investigation. 4: 274-95.