Anti-AMIGO2 Antibody

Cat: 13735-RP01
Contact us:
+86-400-890-9989
order@sinobiological.com
Distributors
All AMIGO2 Reagents
CRO Services
Product recommended

All AMIGO2 Reagents
Anti-AMIGO2 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-AMIGO2 Antibody
Validated applications
ELISA
Species reactivity
Reacts with: Human
Specificity
Human AMIGO2
Immunogen
Recombinant Human AMIGO2 protein (Catalog#13735-H08H)
Preparation
Produced in rabbits immunized with purified, recombinant Human AMIGO2 (rh AMIGO2; Catalog#13735-H08H; NP_862830.1; Met1-Thr398). Total IgG was purified by Protein A affinity chromatography.
Source
Polyclonal Rabbit IgG
Purification
Protein A
Formulation
0.2 μm filtered solution in PBS with 5% trehalose
Conjugate
Unconjugated
Form
Liquid
Shipping
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-AMIGO2 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-AMIGO2 Antibody Alternative Names
Anti-ALI1 Antibody;Anti-AMIGO-2 Antibody;Anti-DEGA Antibody
AMIGO2 Background Information

AMIGO2 contains Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. It belongs to the immunoglobulin superfamily, AMIGO family. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. It is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may also contribute to signal transduction through its intracellular domain. It may play a role in the tumorigenesis of a subset of gastric adenocarcinomas. AMIGO2 is highly expressed in breast, ovary, cervix, and uterus.

Full Name
adhesion molecule with Ig-like domain 2
References
  • Rouhiainen A, et al. (2003) AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. J Cell Biol. 160:963-73.
  • Kikkawa Y, et al. (2003) Alivin 1, a novel neuronal activity-dependent gene, inhibits apoptosis and promotes survival of cerebellar granule neurons. J Neurosci. 23:5887-96.
  • Bassi R, et al. (2004) DEGA/AMIGO-2, a leucine-rich repeat family member, differentially expressed in human gastric adenocarcinoma: effects on ploidy, chromosomal stability, cell adhesion/migration and tumorigenicity. Oncogene 23:5056-67.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-AMIGO2 Antibody Rabbit Polyclonal ELISA,IHC-P 13735-T16
    info info
    添加购物车成功! 添加购物车失败!