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ALK-7 / ACVR1C

ALK-7 / ACVR1C Protein & Antibody

ACVR1C Related Information

ALK-7 / ACVR1CN


ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

OMIM-Description for ALK-7 / ACVR1CN


ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001).

ALK-7 / ACVR1C


The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD family transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
ACVR1C transduces signals of Nodal. Nodal binds to ACVR2B and then forms a comlex with ACR1C. These go on to recruit the R-SMADs SMAD2 or SMAD3.

ALK-7 / ACVR1C Alternative Names

ALK-7 / ACVR1C Related Products

ALK-7 / ACVR1C Proteins

Product nameProduct name
Human ALK-7 / ACVR1C Protein (ECD, Fc Tag)Cynomolgus ALK-7 / ALK7 / ACVR1C Protein (Fc Tag)

ALK-7 / ACVR1C Antibodies

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ALK-7 / ACVR1C cDNA Clones

Product nameProduct name
Cynomolgus monkey ACVR1C Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedCynomolgus monkey ACVR1C Gene cDNA Clone (full-length ORF Clone), expression ready, His-taggedCynomolgus monkey ACVR1C Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedCynomolgus monkey ACVR1C Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedCynomolgus monkey ACVR1C Gene cDNA Clone (full-length ORF Clone), expression ready, HA-taggedHuman ACVR1C / ALK-7 Gene cDNA Clone (full-length ORF Clone)Human ACVR1C / ALK-7 Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-taggedHuman ACVR1C / ALK-7 Gene cDNA Clone (full-length ORF Clone), expression ready, His-taggedHuman ACVR1C / ALK-7 Gene cDNA Clone (full-length ORF Clone), expression ready, Myc-taggedHuman ACVR1C / ALK-7 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedCynomolgus monkey ACVR1C Gene cDNA Clone (full-length ORF Clone)

ALK-7 / ACVR1C ELISA

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"