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ALK-7 / ACVR1C

ALK-7 / ACVR1C Protein & Antibody

ACVR1C Related Information

Entrez Gene Summary for ALK-7 / ACVR1C


ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

OMIM-Description for ALK-7 / ACVR1C


ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001).

.zh=ALK-7 / ACVR1C


The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. ACVR1C is a type I receptor for the TGFB family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD family transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.
ACVR1C transduces signals of Nodal. Nodal binds to ACVR2B and then forms a comlex with ACR1C. These go on to recruit the R-SMADs SMAD2 or SMAD3.

ALK-7 / ACVR1C Alternative Names

ALK-7 / ACVR1C Related Products

ALK-7 / ACVR1C Proteins

Product nameProduct name
Human ALK-7 / ACVR1C Protein (ECD, Fc Tag)Rhesus ALK-7 / ALK7 / ACVR1C Protein (Fc Tag)

ALK-7 / ACVR1C Antibodies

Product nameProduct name

ALK-7 / ACVR1C cDNA Clones

Product nameProduct name
Human ACVR1C / ALK-7 ORF mammalian expression plasmid, C-Flag tagRhesus ACVR1C ORF mammalian expression plasmid, C-Flag tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, C-GFPSpark tagRhesus ACVR1C ORF mammalian expression plasmid, C-Myc tagRhesus ACVR1C ORF mammalian expression plasmid, N-Myc tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, N-Myc tagRhesus ACVR1C ORF mammalian expression plasmid, N-His tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, N-His tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, C-OFPSpark / RFP tagHuman ACVR1C / ALK-7 Gene cDNA clone plasmidRhesus ACVR1C ORF mammalian expression plasmid, C-OFPSpark / RFP tagHuman ACVR1C / ALK-7 natural ORF mammalian expression plasmidRhesus ACVR1C natural ORF mammalian expression plasmidHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, C-Myc tagRhesus ACVR1C ORF mammalian expression plasmid, N-Flag tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, N-Flag tagHuman ACVR1C / ALK-7 Gene cDNA Clone (full-length ORF Clone), expression ready, untaggedRhesus ACVR1C ORF mammalian expression plasmid, N-HA tagRhesus ACVR1C ORF mammalian expression plasmid, C-HA tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, N-HA tagRhesus ACVR1C Gene cDNA clone plasmidHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, C-HA tagRhesus ACVR1C ORF mammalian expression plasmid, C-His tagHuman ACVR1C / ALK-7 ORF mammalian expression plasmid, C-His tagRhesus ACVR1C ORF mammalian expression plasmid, C-GFPSpark tag

ALK-7 / ACVR1C ELISA

Product nameProduct name
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