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Product Catalog
> ALK-1 Protein (ALK1, ACVRL1 Protein) ALK-1 Protein (ALK1, ACVRL1 Protein)
Activin Receptor-Like Kinase 1 (Activin A Receptor, type II-Like 1)
ALK-1 Protein & Antibody
ALK-1 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| ALK-1 | Human | ALK-1/Fc Protein, Recombinant | 10066-H02H |
| ALK-1 | Human | ALK-1 Protein, Recombinant | 10066-H08H |
| ALK-1 | Mouse | ALK-1/Fc Protein, Recombinant | 50208-M03H |
ALK-1 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| ALK-1 | Mouse | Mus musculus ALK-1 cDNA Clone | MG50208-M |
All ALK-1 Protein and Antibody
ALK-1 Alternative Names
ALK-1, ALK1, ACVRL1, ACVRLK1, HHT, HHT2, ORW2, SKR3, TSR-I [ Homo sapiens ]
ALK-1, ALK1, ACVRL1, ACVRLK1, AI115505, AI427544 [ Mus musculus ]
ALK-1 Related Areas
Neuroscience>>Axon Guidance>>TGF-beta Family>>ALK-1 / ACVRL1
Cancer>>Growth Factor & Receptor>>TGF-beta Superfamily>>Activin/Inhibitin>>ALK-1 / ACVRL1
Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>>TGF-beta Family>>ALK-1 / ACVRL1
Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>>TGF-beta Superfamily Receptors>>ALK-1 / ACVRL1
ALK-1 Protein Related Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| TGF-beta 1 | Human | Latent TGFβ1 protein, Recombinant |
| TGFβR2 | Human | TGFβR2/Fc Protein, Recombinant |
| BAMBI/NMA | Human | BAMBI/NMA Protein, Recombinant |
| Decorin | Human | Decorin/Fc Protein, Recombinant |
| Decorin | Human | Decorin Protein, Recombinant |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Human TGF-beta 1 |
WB | Mouse Monoclonal Antibody |
| Human TGF-beta 1 |
ELISA | Mouse Monoclonal Antibody |
| Human TGF-beta 1 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Human TGF-beta 1 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human BAMBI/NMA |
WB | BAMBI/NMA Antibody, Mouse MAb |
| Human BAMBI/NMA |
ELISA | BAMBI/NMA Antibody, Mouse MAb |
| Human BAMBI/NMA |
WB, ELISA | BAMBI/NMA Antibody, Rabbit PAb |
| Human BAMBI/NMA |
WB, ELISA | BAMBI/NMA Antibody, Rabbit PAb (Antigen Affinity Purified) |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| TGF-beta 1 | Human | Homo sapiens TGF-beta 1 cDNA Clone(NM_000660.3) |
| TGF-beta 2 | Human | Homo sapiens TGF-beta 2 transcript variant 2 cDNA Clone(NM_003238.2) |
| TGF-beta 2 | Mouse | Mus musculus TGF-beta 2 cDNA Clone |
| TGF-beta 3 | Human | Homo sapiens TGF-beta 3 cDNA Clone |
| TGF-beta 3 | Mouse | Mus musculus TGF-beta 3 cDNA Clone |
| ALK-1 | Human | Homo sapiens ALK-1/ACVRL1 transcript variant 1 cDNA Clone(NM_000020.2) |
| ALK-7 | Human | Homo sapiens ALK-7 cDNA Clone(NM_145259.2) |
| TGFBR1/ALK-5 | Human | Homo sapiens TGFBR1/ACVRLK4 cDNA Clone(NM_004612.2) |
| TGFBR1/ALK-5 | Mouse | Mus musculus TGFBR1/ALK-5 cDNA Clone |
| TGFβR2 | Human | Homo sapiens TGFβR2 transcript variant 2 cDNA Clone(NM_003242.5) |
| BAMBI/NMA | Human | Homo sapiens BAMBI/NMA cDNA Clone |
| Smad1 | Human | Homo sapiens Smad1 cDNA Clone(NM_001003688.1) |
| Smad2 | Human | Homo sapiens SMAD2 transcript variant 2 cDNA Clone(NM_001003652.2) |
| Smad3 | Human | Homo sapiens Smad3 cDNA Clone(NM_005902.3) |
ALK-1 Background
Activin receptor-like kinase 1 (ALK-1), also known as Activin A receptor and type II-like 1 (ACVRL1), is a type I cell-surface receptor for the TGF-beta superfamily. ALK-1 has been suggested to be implicated in the blood vessel development and repair. Mutations in this gene are associated with hemorrhagic telangiectasia type 2 (HHT2), also known as Rendu-Osler-Weber syndrome 2 (ORW2). In cultured endothelial cells, ALK-1 and another TGF-beta type I receptor, ALK-5, regulate angiogenesis by controlling TGF-beta signal transduction, and ALK-5 is required for ALK-1 signaling. Expression of ALK-1 in blood vessels and mutations of the ALK-1 gene in human suggest that it has an important role during vascular development.
ALK-1 Related Studies
- Abdalla SA, et al. (2000). Analysis of ALK-1 and endoglin in newborns from families with hereditary hemorrhagic telangiectasia type 2. Hum Mol Genet. 9(8): 1227–37.
- Mo J, et al. (2002) Regulation of ALK-1 signaling by the nuclear receptor LXRbeta. J Biol Chem. 277(52): 50788-94.
- Yan ZM, et al. (2006) A novel mutation in ALK-1 causes hereditary hemorrhagic telangiectasia type 2. J Dent Res. 85(8): 705-10.
