Anti-ALK-1 Antibody

Cat: 10066-MM05
Contact us:
All ALK-1 Reagents
CRO Services
Product recommended

All ALK-1 Reagents
Anti-ALK-1 Antibody (Mouse Monoclonal antibody) General Information
Product name
Anti-ALK-1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human ALK-1
Recombinant Human ALK-1 / ACVRL1 Protein (Catalog#10066-H08H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALK-1 / ACVRL1 (rh ALK-1 / ACVRL1 ; Catalog#10066-H08H; NP_000011.2; Met1-Gln118). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #05
Protein A
PBS, 5% Trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ALK-1 Antibody (Mouse Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-ALK-1 Antibody Alternative Names
Anti-ACVRLK1 Antibody;Anti-ALK-1 Antibody;Anti-ALK1 Antibody;Anti-HHT Antibody;Anti-HHT2 Antibody;Anti-ORW2 Antibody;Anti-SKR3 Antibody;Anti-TSR-I Antibody
ALK-1 Background Information

Activin A receptor, type II-like 1 (ACVRL1), also known as ALK-1 (activin receptor-like kinase 1), is an endothelial-specific type I receptor of the TGF-beta (transforming growth factor beta) receptor family of ligands. On ligand binding, a heteromeric receptor complex forms consisting of two type II and two type I transmembrane serine/threonine kinases. ACVRL1 protein is expressed in certain blood vessels of kidney, spleen, heart and intestine, serving as an important role during vascular development. Mutations in ACVRL1 gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2 and vascular disease.

Full Name
activin A receptor type II-like 1
  • French Rendu-Osler network,et al. (2004) Molecular screening of ALK1/ACVRL1 and ENG genes in hereditary hemorrhagic telangiectasia in France. Hum Mutat. 23(4): 289-299.
  • Simon M, et al. (2006) Association of a polymorphism of the ACVRL1 gene with sporadic arteriovenous malformations of the central nervous system. J Neurosurg. 104(6): 945-9.
  • Argyriou L, et al. (2006) Novel mutations in the ENG and ACVRL1 genes causing hereditary hemorrhagic teleangiectasia. Int J Mol Med. 17(4):655-9.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-ALK-1 Antibody Rabbit Polyclonal ELISA 90060-RP01
    Anti-ALK-1 Antibody Rabbit Polyclonal WB,ELISA 90060-T48
    Anti-ALK-1 Antibody Rabbit Monoclonal ELISA,ELISA(Det) 10066-R024
    Anti-ALK-1 Antibody Rabbit Monoclonal ELISA(Cap) 10066-R104
    Anti-ALK-1 Antibody Rabbit Polyclonal ELISA 10066-RP01
    Anti-ALK-1 Antibody Rabbit Polyclonal WB,ELISA,IHC-P 10066-RP02
    Anti-ALK-1 Antibody Rabbit Monoclonal WB,IP 10066-R124
    info info
    添加购物车成功! 添加购物车失败!