ALDOB / Aldolase B Protein Price Inquiry ( Available Sizes )
ALDOB / Aldolase B Protein Product Information
||RP11-490D19.1, ALDB, ALDO2
||A DNA sequence encoding the human ALDOB (P05062) (Ala 2-Tyr 364) was fused with the GST tag at the N-terminus.
ALDOB / Aldolase B Protein QC Testing
||>88% as determined by SDS-PAGE.
ALDOB / Aldolase B protein
||Please contact us for more information.
||Samples are stable for up to twelve months from date of receipt at -70℃
|Predicted N terminal:
||The recombinant human ALDOB/GST chimera consists of 597 amino acids and has a predicted molecular mass of 66.5 kDa. It migrates as an approxiamtely 60 KDa band in SDS-PAGE under reducing conditions.
||Lyophilized from sterile PBS, pH7.5
- Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.
- Please contact us for any concerns or special requirements.
ALDOB / Aldolase B Protein Usage Guide
||Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
||A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
ALDOB / Aldolase B Protein Related Products & Topics
ALDOB / Aldolase B Protein Description
Aldolase B (ALDOB), also known as fructose-bisphosphate aldolase B or liver-type aldolase, is an important enzyme classified into isoenzymes (A, B, and C) of the class Ⅰfructose 1,6-bisphosphate aldolase enzyme, and plays a key role in both glycolysis and gluconeogenesis. Aldolase B is composed of four subunits. Each subunit has a molecular weight of about 36kDa and contains an eight-stranded α/β barrel, which encloses lysine 229. Aldolase B plays a key role in carbohydrate metabolism as it catalyzes one of the major steps of the glycolytic-gluconeogenic pathway. Genetic mutatons leading to defects in aldolase B results in a condition called hereditary fructose intolerance. This homotetrameric enzyme contribute to catalyze the reversible reaction of fructose 1,6-bisphosphate(FBP) into glyceraldehyde 3-phosphate and dihydroxyacetone phosphate (DHAP) as well as the reversible cleavage of fructose 1-phosphate (F1P) into glyceraldehydes and dihydroxyacetone phosphate.
- Cox TM. 1994, FASEB J. 8(1): 62-71.
- Malay AD. et al., 2005, J Mol Biol. 347 (1): 135-44.
- Susan PP. et al., 2001, J Cell Physiol. 187 (1): 48-58.