ALDH7A1 Protein & Antibody

Aldehyde dehydrogenase 7 family, member A1

ALDH7A1 Products

ALDH7A1 Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
ALDH7A1	Human	ALDH7A1 Protein, Recombinant	11614-H07E

ALDH7A1 Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human ALDH7A1	WB, ELISA	ALDH7A1 Antibody, Rabbit PAb	11614-RP01
Human ALDH7A1	WB, ELISA	ALDH7A1 Antibody, Rabbit PAb (Antigen Affinity Purified)	11614-RP02
Human ALDH7A1	WB	ALDH7A1 Antibody	11614-MM04
Human ALDH7A1	ELISA	ALDH7A1 Antibody	11614-R105

ALDH7A1 cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
ALDH7A1	Human	Homo sapiens ALDH7A1 cDNA Clone	HG11614-M

ALDH7A1 Related Areas

Alcohol Metabolism>>ALDH7A1

ALDH7A1 Alternative Names

ALDH7A1, ATQ1, EPD, FLJ11738, FLJ92814, PDE, antiquitin 1, antiquitin-1 [Homo sapiens]

Aldh7a1, Atq1, D18Wsu181e, antiquitin 1, antiquitin-1 [Mus musculus]

ALDH7A1 Background

ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.

ALDH7A1 Related Studies

1. Brocker C, et al. (2011) Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. Chem Biol Interact. 191(1-3): 269-77.
2. Brocker C, et al. (2010) Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. J Biol Chem. 285(24): 18452-63.