All ALDH7A1 reagents are produced in house and quality controlled, including 9 ALDH7A1 Antibody, 43 ALDH7A1 Gene, 2 ALDH7A1 IPKit, 1 ALDH7A1 Protein, 2 ALDH7A1 qPCR. All ALDH7A1 reagents are ready to use.
Recombinant ALDH7A1 proteins are expressed by E. coli with fusion tags as N-His.
ALDH7A1antibodies are validated with different applications, which are IHC-P, FCM, WB, ELISA, IP, ICC/IF, IF.
ALDH7A1cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ALDH7A1 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.