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ALDH7A1 Antibody, Mouse MAb

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Human ALDH7A1 Antibody Product Information
Immunogen:Recombinant Human ALDH7A1 protein (Catalog#11614-H07E)
Clone ID:04
Ig Type:Mouse IgG1
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS with 5% trehalose
Preparation:This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ALDH7A1 (rh ALDH7A1; Catalog#11614-H07E; P49419-2; Ser 2-Gln 511). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Human ALDH7A1 Antibody WB Application Image
Other ALDH7A1 Antibody Products
Reactivity: Human  
Application: FCM  
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11614-R101-F-25
11614-R101-F-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: ELISA  WB  IP  
  • Slide 1
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11614-R105-50
11614-R105-100
50 µg 
100 µg 
Add to Cart
Reactivity: Human  
Application: FCM  
  • Slide 1
11614-R101-P-25
11614-R101-P-100
25 Test 
100 Tests 
Add to Cart
Reactivity: Human  
Application: ELISA  
    11614-MM02-50
    11614-MM02-200
    11614-MM02-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: FCM  IF  ICC/IF  
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    11614-R101-50
    11614-R101-100
    50 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: IHC-P  
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    • Slide 1
    11614-MM11-50
    11614-MM11-200
    11614-MM11-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  WB  IHC-P  IP  
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    11614-RP02-50
    11614-RP02-200
    11614-RP02-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    Reactivity: Human  
    Application: ELISA  
      11614-RP01-400
      11614-RP01-200
      11614-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart
      Immunochemical staining of human CCNF in human brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections).
      ALDH7A1 Background

      ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.

      Human ALDH7A1 References
    • Brocker C, et al. (2011) Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity. Chem Biol Interact. 191(1-3): 269-77.
    • Brocker C, et al. (2010) Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress. J Biol Chem. 285(24): 18452-63.
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