ALDH3A1 Protein

Aldehyde dehydrogenase 3 family, member A1

ALDH3A1 Products

ALDH3A1 Protein, Recombinant

Molecule	Species	Description	Cat. No
ALDH3A1	Human	ALDH3A1 Protein, Recombinant	12523-H07B

ALDH3A1 cDNA Clone

Molecule	Species	Description	Cat. No
ALDH3A1	Human	ALDH3A1 cDNA Clone / ORF Clone	HG13129-G

ALDH3A1 Related Areas

Alcohol Metabolism>>ALDH3A1

ALDH3A1 Alternative Names

ALDH3A1, ALDH3, ALDHIII, MGC10406 [Homo sapiens]

Aldh3a1, RP23-55I2.1, Ahd-4, Ahd4, Aldh, Aldh3 [Mus musculus]

ALDH3A1 Background

Aldehyde dehydrogenases(ALDH)are a group of proteins that take part in the oxidation of aldehydes to the corresponding acids which leave the liver and metabolized in the body's heart and muscle. There are three kinds of Aldehyde dehydrogenas in mammals: ALDH1, ALDH2 and ALDH3. Aldehyde dehydrogenase 3A1(ALDH3A1), which belongs to the ALDH3 subfamily, was found to be widely distributed in the mammal's corneal and is believed to protect against the UV-induced oxidative damage. Human ALDH3A1 demonstrated high substrate specificity for medium-chain saturated and unsaturated aldehydes and immunohistochemisty in human corneas suggested ALDH3A1 expression in epithelial cells and stromal keratocytes, but not in endothelial cells.

ALDH3A1 Related Studies

1. Pappa A, et al. (2003) Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea. Biochem J. 376(3): 615–23.
2. Estey T, et al. (2007) ALDH3A1: a corneal crystallin with diverse functions. Experimental Eye Research. 84(1):3-12.
3. Pappa A, et al. (2003) Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage. Free Radical Biology and Medicine. 34(9):1178-89.