Text Size:AAA

AGO3 Protein, Antibody, ELISA Kit, cDNA Clone

AGO3 Related Areas

AGO3 Related Pathways

AGO3 Related Product

    AGO3 Summary & Protein Information

    AGO3 Background

    Gene Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
    General information above from NCBI
    Subunit structure: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H. Interacts with EDC4.
    Domain: The di-leucine motif mediates lysosomal localization (PubMed:22822152).
    Subcellular location: Cytoplasm, P-body.
    Sequence similarity: Belongs to the argonaute family. Ago subfamily.
    Contains 1 PAZ domain.
    Contains 1 Piwi domain.C
    General information above from UniProt

    AGO3 Alternative Name

    AGO3 Related Studies

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"