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AGO3 Protein, Antibody, ELISA Kit, cDNA Clone

AGO3 Related Areas

AGO3 Related Pathways

AGO3 Related Protein, Antibody, cDNA Gene, and ELISA Kits

AGO3 Summary & Protein Information

AGO3 Background

Gene Summary: This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.
General information above from NCBI
Subunit structure: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H. Interacts with EDC4.
Domain: The di-leucine motif mediates lysosomal localization (PubMed:22822152).
Subcellular location: Cytoplasm, P-body.
Sequence similarity: Belongs to the argonaute family. Ago subfamily.
Contains 1 PAZ domain.
Contains 1 Piwi domain.C
General information above from UniProt

AGO3 Alternative Name

AGO3 Related Studies

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