AFP / alpha-fetoprotein Protein & Antibody

Alpha-fetoprotein

AFP Products

AFP Protein, Recombinant

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
AFP	Human	AFP / alpha-fetoprotein Protein,Recombinant	12177-H08H

AFP Antibody

Molecule	Application	Description //For Detailed Info. and Price------CLICK!	Cat. No
Human AFP	WB, ELISA	AFP / alpha-fetoprotein Antibody	12177-MM10
Human AFP	ELISA	AFP / alpha-fetoprotein Antibody	12177-MM15

AFP cDNA Clone

Molecule	Species	Description //For Detailed Info. and Price------CLICK!	Cat. No
AFP	Human	AFP cDNA Clone / ORF Clone	HG12177-G

AFP Related Areas

Cancer>>Cancer Biomarkers>>AFP

AFP Alternative Names

FETA, HPAFP[Homo sapiens]

alpha-1-fetoprotein,alpha-fetoglobulin, alpha-fetoprotein,alpha-foetoprotein[Mus musculus]

AFP Background

Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moiety. AFP is one of the several embryo-specific proteins and is a dominant serum protein as early in human embryonic life as one month, when albumin and transferrin are present in relatively small amounts. It is first synthesized in the human by the yolk sac and liver(1-2 months) and subsequently predominantly in the liver. A small amount of AFP is produced by the GI tract of the human conceptus. It has been proved that AFP may reappear in the serum in elevated amounts in adult life in association with normal restorative processes and with malignant growth. Alpha-fetoprotein (AFP) is a specific marker for hepatocellular carcinoma (HCC), teratoblastomas, and neural tube defect (NTD).

AFP Related Studies

1. Mizejewski GJ. (2001) Alpha-fetoprotein Structure and Function: Relevance to Isoforms, Epitopes, and Conformational Variants. Exp Biol Med. 226(5): 377-408.
2. Tomasi TB, et al. (1977) Structure and Function of Alpha-Fetoprotein. Annual Review of Medicine. 28: 453-65.
3. Leguy MC, et al. (2011) Assessment of AFP in amniotic fluid: comparison of three automated techniques. Ann Biol Clin. 69(4): 441-6.