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ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb

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Human ADSL Antibody Product Information
Immunogen:Recombinant Human ADSL / Adenylosuccinate Lyase protein (Catalog#11287-H07E)
Clone ID:007
Ig Type:Rabbit IgG
Concentration:
Endotoxin:
Formulation:0.2 μm filtered solution in PBS
Preparation:This antibody was obtained from a rabbit immunized with purified, recombinant Human ADSL / Adenylosuccinate Lyase (rh ADSL / Adenylosuccinate Lyase; Catalog#11287-H07E; P30566-1; Met1-Leu484).
Human ADSL Antibody WB Application Image
Human ADSL Antibody IHC Application Image
ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
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Caption:
Immunochemical staining of human ADSL in human ovarian cancer with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections).
ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
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Caption:
Immunochemical staining of human ADSL in human small intestine with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections).
ADSL / Adenylosuccinate Lyase Antibody, Rabbit MAb, Immunochemistry
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Caption:
Immunochemical staining of human ADSL in human thyroid with rabbit monoclonal antibody (2 µg/mL, formalin-fixed paraffin embedded sections).
Human ADSL Antibody IP Application Image
Other ADSL Antibody Products
Flow cytometric analysis of Mouse LILRB3(CD85a) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse LILRB3(CD85a), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
ADSL / Adenylosuccinate Lyase Background

Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of adenylosuccinate lyase (ADSL) are dephosphorylated derivatives of SAICA ribotide (SAICAR) and adenylosuccinate (S-AMP), which catalyzes an important reaction in the de novo pathway of purine biosynthesis. ADSL catalyzes two distinct reactions in the synthesis of purine nucleotides, both of which involve the _-elimination of fumarate to produce either aminoimidazole carboxamide ribotide from SAICAR or AMP from S-AMP. The Adenylosuccinate lyase deficiency is a rare autosomal recessive metabolic disorder characterized by