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> ADAM9 Protein ADAM9 Protein
ADAM metallopeptidase domain 9
ADAM9 Products
ADAM9 Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| ADAM9 | Mouse | ADAM9 Protein, Recombinant | 50044-M08H |
ADAM9 cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| ADAM9 | Mouse | Mouse ADAM9 cDNA Clone / ORF Clone | MG50044-M |
ADAM9 Related Areas
Enzyme>>Protease & Regulator>>Metalloprotease & Regulator>>ADAM / ADAMTS>>ADAM9
Cancer>>Angiogenesis>>ADAM / ADAMTS>>ADAM9
ADAM9 Alternative Names
ADAM9, CORD9, KIAA0021, MCMP, MDC9, Mltng [Homo sapiens]
Adam9, AU020942, MDC9, Mltng, mKIAA0021 [Mus musculus]
ADAM9 Related Products
Protein Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| ADAM12 | Human | ADAM12 Protein, Recombinant |
| ADAM15 | Human | ADAM15 Protein, Recombinant |
| ADAM15 | Mouse | ADAM15 Protein, Recombinant |
Antibody Products
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! |
| Human ADAM12 |
WB, ELISA | Mouse Monoclonal Antibody |
| Human ADAM12 |
ELISA | Rabbit Monoclonal Antibody |
| Human ADAM12 |
WB, ELISA | Rabbit Polyclonal Antibody |
| Human ADAM12 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human ADAM15 |
WB, ELISA | Rabbit Monoclonal Antibody |
| Human ADAM15 |
WB, ELISA | Rabbit Polyclonal Antibody (Antigen Affinity Purified) |
| Human ADAM15 |
WB, ELISA | Rabbit Polyclonal Antibody |
cDNA Clone Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| ADAM8/CD156 | Human | Homo sapiens ADAM8/CD156 cDNA Clone(NM_001109.3) |
| ADAM9 | Mouse | Mus musculus ADAM9 cDNA Clone |
| ADAM12 | Human | Homo sapiens ADAM12 cDNA Clone |
| ADAM15 | Human | Homo sapiens ADAM15 cDNA Clone(NM_207191.1) |
| ADAMTS1 | Human | Homo sapiens ADAMTS1 cDNA Clone(NM_006988.3) |
| ADAMTS4 | Human | Homo sapiens ADAMTS4 cDNA Clone(NM_005099.3) |
| ADAMTS5 | Human | Homo sapiens ADAMTS5 cDNA Clone(NM_007038.3) |
ADAM9 Background
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential therapeutic target in tumors where it is highly expressed. ADAM9 belongs to a family of transmembrane, disintegrin-containing metalloproteinases involved in protein ectodomain shedding and cell-cell and cell-matrix interactions. ADAM-9 adhesive domain plays a role in regulating the motility of cells by interaction with beta1 integrins and modulates MMP synthesis.
ADAM9 Related Studies
- Caltabiano R, et al. (2011) ADAM-9 expression in intestinal-type adenocarcinoma of the sinonasal tract. Appl Immunohistochem Mol Morphol. 19(3): 283-7.
- Peduto L. (2009) ADAM9 as a potential target molecule in cancer. Curr Pharm Des. 15(20): 2282-7.
- Zigrino P, et al. (2007) Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration. J Biol Chem. 282(42): 30785-93.
