All ADAM8 reagents are produced in house and quality controlled, including 2 ADAM8 Antibody, 13 ADAM8 Gene, 1 ADAM8 Lysate, 1 ADAM8 Protein, 1 ADAM8 qPCR. All ADAM8 reagents are ready to use.
Recombinant ADAM8 proteins are expressed by HEK293 Cells with fusion tags as C-His.
ADAM8antibodies are validated with different applications, which are IHC-P, ICC/IF, IF.
ADAM8cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each ADAM8 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
ADAM8, also known as CD156, is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM8 is possiblely involved in extravasation of leukocytes As a metalloprotease, ADAM8 also may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma.