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> ACVR2A Protein & Antibody ACVR2A Protein & Antibody
Activin A Receptor, type IIA
ACVR2A Products
ACVR2A Protein, Recombinant
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| ACVR2A | Human | ACVR2A/Fc Protein, Recombinant | 10257-H02H |
| ACVR2A | Human | ACVR2A Protein, Recombinant | 10257-H08H |
| ACVR2A | Mouse | ACVR2A/Fc Protein, Recombinant | 50613-M03H |
| ACVR2A | Mouse | ACVR2A Protein, Recombinant | 50613-M08H |
ACVR2A Antibody
| Molecule | Application | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| Human ACVR2A | WB, ELISA | ACVR2A Antibody | 10257-RP01 |
| Human ACVR2A | WB, ELISA | ACVR2A Antibody (Antigen Affinity Purified) | 10257-RP02 |
ACVR2A cDNA Clone
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! | Cat. No |
| ACVR2A | Human | Homo sapiens ACVR2A cDNA Clone(NM_001616.3) | HG10257-M |
| ACVR2A | Mouse | Mus musculus ACVR2A cDNA Clone | MG50613-M |
| ACVR2A | Cynomolgus | ACVR2A cDNA Clone / ORF Clone | KG90059-G |
ACVR2A Alternative Names
ACVR2A, ACVR2, ACTRII [Homo sapiens]
Acvr2a, ActrIIa, Acvr2, RP23-139F8.3, TactrII [Mus musculus]
ACVR2A Related Areas
Cancer>>Growth Factor & Receptor>>TGF-beta Superfamily>>Activin/Inhibitin>>ACVR2A
Immunology>>Cytokine & Receptor>>TGF-beta Superfamily>>TGF-beta Superfamily Receptors>>ACVR2A
ACVR2A Related Products
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Inhibin beta A/INHBA | Human | Inhibin beta A/INHBA Protein, Recombinant |
| Inhibin beta B/INHBB | Human | Inhibin beta B/INHBB Protein, Recombinant |
| ALK-2/ACVR1 | Human | ALK-2/ACVR1/Fc Protein, Recombinant |
| ALK-2/ACVR1 | Mouse | ALK-2/ACVR1/Fc Protein, Recombinant |
| ACVR2B | Human | ACVR2B/Fc Protein, Recombinant |
| ACVR2B | Human | ACVR2B Protein, Recombinant |
| ACVR2B | Mouse | ACVR2B/Fc Protein, Recombinant |
| ACVR2B | Mouse | ACVR2B Protein, Recombinant |
| FSTL1/Follistatin Like 1 | Human | FSTL1 Protein, Recombinant |
| FLRG/FSTL3 | Mouse | FLRG/FSTL3 Protein, Recombinant |
| Molecule | Species | Description //For Detailed Info. and Price------CLICK! |
| Inhibin alpha/INHA | Human | Homo sapiens Inhibin alpha/INHA cDNA Clone(NM_002191.2) |
| Inhibin beta A/INHBA | Human | Homo sapiens Inhibin beta A/INHBA cDNA Clone(NM_002192.2) |
| Inhibin beta B/INHBB | Human | Homo sapiens Inhibin beta B/INHBB cDNA Clone(NM_002193.2) |
| Inhibin beta C/INHBC | Human | Homo sapiens Inhibin beta C/INHBC cDNA Clone(NM_005538.2) |
| Inhibin beta E/INHBE | Human | Homo sapiens Inhibin beta E/INHBE cDNA Clone(NM_031479.3) |
| ALK-2/ACVR1 | Human | Homo sapiens ALK-2/ACVR1 transcript variant 2 cDNA Clone(NM_001111067.2) |
| ALK-4/ACVR1B | Human | Homo sapiens ALK-4/ACVR1B cDNA Clone(NM_004302.3) |
| ACVR2B | Human | Homo sapiens ACVR2B cDNA Clone(NM_001106.3) |
| Follistatin | Human | Homo sapiens Follistatin cDNA Clone(NM_013409.1) |
| FSTL1/Follistatin Like 1 | Human | Homo sapiens FSTL1 cDNA Clone(NM_007085.4) |
ACVR2A Background
ACVR2A and ACVR2B are two activin type II receptors. ACVR2A has been shown to interact with INHBA, SYNJ2BP and ACVR1B. The bovine ACVR2A gene encodes a protein of 513 amino acids which is highly homologous (approximately 98% identity) to the rat, mouse, and human ACVR2A proteins. Inactivation of ACVR2A is a common event in prostate cancer cells suggesting it may play an important role in the development of prostate cancer. The ACVR2A gene is a putative tumor suppressor gene that is frequently mutated in microsatellite-unstable colon cancers (MSI-H colon cancers). Frameshift mutation of ACVR2A may contribute to MSI-H colon tumorigenesis via disruption of alternate TGF-beta effector pathways.
ACVR2A Related Studies
- Albertson RC, et al. (2005) Zebrafish acvr2a and acvr2b exhibit distinct roles in craniofacial development. Developmental dynamics 233(4): 1405-18.
- Chung H, et al. (2008) Mutation rates of TGFBR2 and ACVR2 coding microsatellites in human cells with defective DNA mismatch repair. PloS one 3(10): e3463.
- Fitzpatrick E, et al. (2009) Genetic association of the activin A receptor gene (ACVR2A) and pre-eclampsia. Molecular human reproduction 15(3):195-204.
- Roten LT, et al. (2009) Association between the candidate susceptibility gene ACVR2A on chromosome 2q22 and pre-eclampsia in a large Norwegian population-based study (the HUNT study). EJHG. 17(2): 250-7.
