Anti-SP-10 Antibody

Cat: 11789-RP01
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All SP-10 Reagents
Anti-SP-10 Antibody (Rabbit Polyclonal antibody) General Information
Product name
Anti-SP-10 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human SP-10
Recombinant Human ACRV1 protein (Catalog#11789-H08H)
Produced in rabbits immunized with purified, recombinant Human ACRV1 (rh ACRV1; Catalog#11789-H08H, P26436-1, Gln 22-Ile 265). Total IgG was purified by Protein A affinity chromatography.
Polyclonal Rabbit IgG
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-SP-10 Antibody (Rabbit Polyclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:1000-1:2000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-SP-10 Antibody Alternative Names
Anti-D11S4365 Antibody;Anti-SP-10 Antibody;Anti-SPACA2 Antibody
SP-10 Background Information

Acrosomal protein SP-10, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest transcript of ACRV1 / SP-10 is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for < 1% of the total acrosomal vesicle protein 1 message. ACRV1 / SP-10 is a testis-specific acrosomal protein that has been detected in several species including humans. It may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. ACRV1 / SP-10 may be involved in sperm-zona binding or penetration. It is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception.

Full Name
acrosomal vesicle protein 1
  • Wright RM, et al.,1990, Biol Reprod. 42 (4): 693-701.
  • Kurth,B.E. et al., 1993, Anat Rec. 236 (4):619-25.
  • Golden WL, et al.,1994, Genomics.18 (2): 446-9. 
  • Foster,J.A. et al., 1994, Biol Reprod. 51 (6):1222-31.
  • Abhyankar,M.M. et al., 2007, J Biol Chem. 282 (50): 36143-54.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-SP-10 Antibody Mouse Monoclonal ELISA(Cap) 11789-MM01
    Anti-SP-10 Antibody Mouse Monoclonal ELISA,ELISA(Det) 11789-MM06
    Anti-SP-10 Antibody Rabbit Polyclonal ELISA,IHC-P 11789-RP02
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