Anti-ACOX1 Antibody

Cat: 11266-R102
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Anti-ACOX1 Antibody (Rabbit Monoclonal antibody) General Information
Product name
Anti-ACOX1 Antibody
Validated applications
Species reactivity
Reacts with: Human
Human ACOX1
Recombinant Human ACOX1 / AOX protein (Catalog#11266-H07B)
This antibody was obtained from a rabbit immunized with purified, recombinant Human ACOX1 / AOX (rh ACOX1 / AOX; Catalog#11266-H07B; AAH08767.1; Met1-Leu660).
Monoclonal Rabbit IgG Clone #102
Protein A
0.2 μm filtered solution in PBS with 5% trehalose
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Anti-ACOX1 Antibody (Rabbit Monoclonal antibody) Validated Applications
Application Dilution Notes
ELISA 1:5000-1:10000  

**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********

Anti-ACOX1 Antibody Alternative Names
Anti-ACOX Antibody;Anti-PALMCOX Antibody;Anti-SCOX Antibody
ACOX1 Background Information

Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a protein of 661-amino acids, including the carboxyl-terminal sequence(Ser-Lys-Leu) known as a minimal peroxisome-targeting signal. Human ACOX1/AOX, the first and rate-limiting enzyme of the peroxisomal β-oxidation pathway, has two isoforms including ACOX1a and ACOX1b, transcribed from a single gene. The human ACOX1b isoform is more effective than the ACOX1a isoform in reversing the Acox1 null phenotype in the mouse partly because of the Substrate utilization differences.

Full Name
acyl-CoA oxidase 1, palmitoyl
  • Vluggens A, et al. (2010) Functional significance of the two ACOX1 isoforms and their crosstalks with PPAR alpha and RXR alpha. Laboratory Investigation. 90: 696-708.
  • Chu R, et al. (1995) Overexpression and characterization of the human peroxisomal acyl-CoA oxidase in insect cells. J Biol Chem. 270 (9): 4908-15.
  • Aoyama T, et al. (1994) Molecular cloning and functional expression of a human peroxisomal acyl-coenzyme A oxidase. Biochem Biophys Res Commun. 198 (3): 1113-8.
  • Product Description Host Clonality Application Catalog# (PDF)
    Anti-ACOX1 Antibody Rabbit Monoclonal IHC-P 11266-R003
    Anti-ACOX1 Antibody Mouse Monoclonal IHC-P 11266-MM09
    Anti-ACOX1 Antibody Rabbit Polyclonal ELISA 11266-RP01
    Anti-ACOX1 Antibody Rabbit Polyclonal ELISA,IHC-P 11266-RP02
    Anti-ACOX1 Antibody Rabbit Monoclonal ELISA 11266-R004
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