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ABP1/AOC1  Protein

All ABP1 Reagents

Expression host: Human Cells  
13623-H08H-20
13623-H08H-100
20 µg 
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ABP1/AOC1 Related Area

ABP1/AOC1 Related Pathways

    ABP1/AOC1 Summary & Protein Information

    ABP1/AOC1 Background

    Catalytic activity: Histamine + H(2)O + O(2) = (imidazol-4-yl)acetaldehyde + NH(3) + H(2)O(2).
    Cofactor: Name=Cu cation; Xref=ChEBI:CHEBI:23378; Evidence={ECO:0000269|PubMed:19764817}; ; Note=Binds 1 copper ion per subunit. {ECO:0000269|PubMed:19764817};; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000269|PubMed:19764817}; ; Note=Binds 2 calcium ions per subunit. {ECO:0000269|PubMed:19764817};; Name=L-topaquinone; Xref=ChEBI:CHEBI:79027; Evidence={ECO:0000269|PubMed:19764817}; ; Note=Contains 1 topaquinone per subunit. {ECO:0000269|PubMed:19764817};
    Subunit structure: Homodimer; disulfide-linked. {ECO:0000269|PubMed:19764817}.
    Subcellular location: Secreted, extracellular space.
    Tissue specificity: Placenta and kidney.
    Post-translational: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
    Sequence similarity: Belongs to the copper/topaquinone oxidase family. {ECO:0000305}.
    General information above from UniProt

    ABP1/AOC1 Alternative Name

    ABP1/AOC1 Related Studies

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