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ABCG2

ABCG2 Protein & Antibody

Entrez Gene Summary for ABCG2


OMIM-Description for ABCG2


The ABCG2 gene encodes a membrane transporter belonging to the ATP-binding cassette (ABC) superfamily of membrane transporters, which are involved in the trafficking of biologic molecules across cell membranes. ABCG2 was initially found to be a xenobiotic transporter that plays a role in the multidrug resistance phenotype of a specific human breast cancer (Doyle et al., 1998) and has since been shown to confer multidrug resistance in several cancer cells by actively exporting a wide variety of drugs across the plasma membrane. The ABCG2 protein is also a high capacity transporter for uric acid excretion in the kidney, liver, and gut (summary from Matsuo et al., 2009 and Saison et al., 2012). For general information on the ABC superfamily, see ABCA4 (601691).

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ATP-binding cassette sub-family G member 2 is a protein that in humans is encoded by the ABCG2 gene. ABCG2 has also been designated as CDw338 (cluster of differentiation w338).

ABCG2 Alternative Names

MRX,MXR,ABCP,BCRP,BMDP,MXR1,ABC15,BCRP1,CD338,GOUT1,CDw338,UAQTL1,EST157481, [homo-sapiens]
MXR,ABCP,BCRP,MXR1,ABC15,Bcrp1,AI428558, [mus-musculus]

ABCG2 Related Products

ABCG2 Proteins

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ABCG2 Antibodies

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ABCG2 cDNA Clones

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Rhesus ABCG2 Gene ORF cDNA clone expression plasmid, C-HA tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, C-His tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, C-Flag tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, N-Myc tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, N-His tagRhesus ABCG2 Gene ORF cDNA clone in cloning vectorRhesus ABCG2 Gene ORF cDNA clone expression plasmidRhesus ABCG2 Gene ORF cDNA clone expression plasmid, N-Flag tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, C-Myc tagRhesus ABCG2 Gene ORF cDNA clone expression plasmid, N-HA tag

ABCG2 ELISA

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