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ABCF1  Protein

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ABCF1 Related Pathways

ABCF1 Summary & Protein Information

ABCF1 Background

Subunit structure: Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes.
Subcellular location: Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
Tissue specificity: Ubiquitous.
Induction: By TNF in cultured synoviocytes.
Post-translational: Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes.
Sequence similarity: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
Contains 2 ABC transporter domains.
General information above from UniProt

ABCF1 Alternative Name

ABC27,ABC50, [homo-sapiens]
Abc50,GCN20,AU041969,D17Wsu166e, [mus-musculus]

ABCF1 Related Studies

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