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ABCF1  Protein, Antibody, ELISA Kit, cDNA Clone

ABCF1 Related Area

ABCF1 Related Pathways

    ABCF1 Summary & Protein Information

    ABCF1 Background

    Subunit structure: Isoform 2 interacts (via N-terminus) with EIF2S1; the interaction is independent of its phosphorylated status. Isoform 2 associates (via both ABC transporter domains) with the ribosomes. {ECO:0000269|PubMed:17894550}.
    Subcellular location: Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope.
    Tissue specificity: Ubiquitous. {ECO:0000269|PubMed:9790762}.
    Induction: By TNF in cultured synoviocytes.
    Post-translational: Isoform 2 is phosphorylated at phosphoserine and phosphothreonine. Isoform 2 phosphorylation on Ser-109 and Ser-140 by CK2; inhibits association of EIF2 with ribosomes. {ECO:0000269|PubMed:17894550}.
    Sequence similarity: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. {ECO:0000305}.; Contains 2 ABC transporter domains. {ECO:0000255|PROSITE-ProRule:PRU00434}.
    General information above from UniProt

    ABCF1 Alternative Name

    ABC27,ABC50, [homo-sapiens]
    Abc50,GCN20,AU041969,D17Wsu166e, [mus-musculus]

    ABCF1 Related Studies

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