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ABCB6  Protein, Antibody, ELISA Kit, cDNA Clone

ABCB6 Related Area

ABCB6 Related Pathways

    ABCB6 Related Protein, Antibody, cDNA Gene, and ELISA Kits

    ABCB6 Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    ABCB6 Summary & Protein Information

    ABCB6 Background

    Subunit structure: Homodimer.
    Subcellular location: Cell membrane. Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus.
    Tissue specificity: Widely expressed. High expression is detected in the retinal epithelium.
    Developmental stage: Highly expressed in fetal liver.
    Induction: Up-regulated by cellular porphyrins (at protein level).
    Involvement in disease: Microphthalmia, isolated, with coloboma, 7 (MCOPCB7) [MIM:614497]: A disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, and other abnormalities may also be present. Ocular colobomas are a set of malformations resulting from abnormal morphogenesis of the optic cup and stalk, and the fusion of the fetal fissure (optic fissure). Note=The disease is caused by mutations affecting the gene represented in this entry.
    Sequence similarity: Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
    General information above from UniProt

    ABCB6 Alternative Name

    ABC,LAN,PRP,DUH3,umat,ABC14,MTABC3,MCOPCB7, [homo-sapiens]
    1200005B17Rik, [mus-musculus]

    ABCB6 Related Studies

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