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Aminoadipate aminotransferase  Protein

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    Aminoadipate aminotransferase Related Protein, Antibody, cDNA Gene, and ELISA Kits

    Aminoadipate aminotransferase Related Protein, Antibody, cDNA Gene, and ELISA Kits

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    Aminoadipate aminotransferase Summary & Protein Information

    Aminoadipate aminotransferase Background

    Catalytic activity: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.; L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.
    Cofactor: Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326; Evidence={ECO:0000269|PubMed:12126930, ECO:0000269|PubMed:18056995, ECO:0000269|PubMed:18056996};
    Enzyme regulation: ENZYME REGULATION: Kynurenine transaminase activity is competitively inhibited by aminoadipate, asparagine, glutamate, histidine, cysteine, lysine, 3-hydroxy-kynurenine and phenylalanine. {ECO:0000269|PubMed:18620547}.
    Subunit structure: Homodimer. {ECO:0000269|PubMed:18056995, ECO:0000269|PubMed:18056996, ECO:0000269|PubMed:18620547}.
    Subcellular location: Mitochondrion {ECO:0000305}.
    Tissue specificity: Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary.
    Sequence similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}.
    General information above from UniProt

    Aminoadipate aminotransferase Alternative Name

    KAT2,KATII, [homo-sapiens]
    Aadt,Kat2,KATII,mKat-2,AI875679, [mus-musculus]

    Aminoadipate aminotransferase Related Studies

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