**********Please Note: Optimal concentrations/dilutions should be determined by the end user.**********
4-1BBL is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In additon, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Immune Checkpoint Detection: Antibodies Immune Checkpoint Detection: ELISA Antibodies Immune Checkpoint Detection: ICC Antibodies Immune Checkpoint Detection: FCM Antibodies
Immune Checkpoint Targets Co-stimulatory Immune Checkpoint Targets
|Product Description||Host||Clonality||Application||Catalog# (PDF)|
|Anti-4-1BBL Antibody (PerCP)||Rabbit||Monoclonal||FCM||50067-R014-C|
|Anti-4-1BBL Antibody (APC)||Rabbit||Monoclonal||FCM||50067-R014-A|
|Anti-4-1BBL Antibody (PE)||Rabbit||Monoclonal||FCM||50067-R014-P|